Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.47 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695692 | 0.84 | CYSLTR1 (0.49) | CYSLTR1GPBAR1CYSLTR2FFAR1AKR1B1 | |
| SCHEMBL10696449 | 0.84 | CYSLTR1 (0.48) | CYSLTR1GPBAR1CYSLTR2ALOX5HDAC1 | |
| SCHEMBL10696181 | 0.77 | ALOX5 (0.69) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL7593150 | 0.76 | GPBAR1 (0.56) | CYSLTR1GPBAR1CYSLTR2ALOX5FFAR1 | |
| SCHEMBL9315704 | 0.74 | CYSLTR1 (0.47) | CYSLTR1CYSLTR2 | |
| SCHEMBL7921075 | 0.74 | GPBAR1 (0.53) | CYSLTR1GPBAR1CYSLTR2ALOX5FFAR1 | |
| SCHEMBL10694503 | 0.73 | CYSLTR1 (0.52) | CYSLTR1GPBAR1CYSLTR2ALOX5FFAR1 | |
| SCHEMBL18530698 | 0.72 | HDAC1 (0.61) | GPBAR1HDAC1HDAC2 | |
| SCHEMBL18530694 | 0.72 | HDAC1 (0.61) | GPBAR1HDAC1HDAC2 | |
| SCHEMBL9582699 | 0.71 | GPBAR1 (0.63) | CYSLTR1GPBAR1CYSLTR2FFAR1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769461-A | Quinolinyl benzene hydroxamic acids as anti-inflammatory/antiallergic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-09-06 | — | — | US | claimed |
| US-4769461-A | Quinolinyl benzene hydroxamic acids as anti-inflammatory/antiallergic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-09-06 | — | — | US | disclosed |