Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693566 | 0.76 | SRD5A2 (0.41) | SRD5A2MAPK1HPGDMAPTCYP1A2 | |
| SCHEMBL10693391 | 0.75 | MAPK1 (0.41) | SRD5A2MAPK1HPGDHRH3MAPT | |
| SCHEMBL809735 | 0.66 | ATM (0.67) | SRD5A2MAPK1HPGDL3MBTL1CNR1 | |
| SCHEMBL5518679 | 0.66 | SRD5A2 (0.61) | SRD5A2MAPK1HPGDCNR1CNR2 | |
| SCHEMBL10697158 | 0.65 | SRD5A2 (0.80) | SRD5A2MAPK1HPGDMAPTL3MBTL1 | |
| SCHEMBL9065412 | 0.65 | SRD5A2 (0.80) | SRD5A2MAPK1HPGDMAPTL3MBTL1 | |
| SCHEMBL1681512 | 0.65 | SRD5A2 (0.80) | SRD5A2MAPK1HPGDMAPTL3MBTL1 | |
| SCHEMBL51827 | 0.65 | SRD5A2 (0.80) | SRD5A2MAPK1HPGDMAPTL3MBTL1 | |
| SCHEMBL9475353 | 0.64 | SRD5A2 (0.59) | SRD5A2MAPK1HPGDCNR1CNR2 | |
| SCHEMBL12274592 | 0.63 | SRD5A2 (0.70) | SRD5A2MAPK1HPGDCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778792-A | Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders | LABORATORIES NEGMA (FR) | 1988-10-18 | — | — | US | disclosed |