Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.58 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.58 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.58 |
| ▸ | ALB | P02768 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | RARB | P10826 | 1/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.58 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.58 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694238 | 0.86 | ALOX5 (0.76) | ALOX5PTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL2334501 | 0.82 | ALOX5 (0.69) | ALOX5PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL10691580 | 0.80 | ALOX5 (0.67) | ALOX5PTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL10875435 | 0.79 | ALOX5 (0.66) | ALOX5PTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL17774456 | 0.76 | ALOX5 (0.60) | ALOX5PTGS1PTGS2LMNAMEN1 | |
| SCHEMBL4480706 | 0.76 | PTGS1 (0.65) | ALOX5PTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL4480653 | 0.76 | PTGS1 (0.65) | ALOX5PTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL2340070 | 0.76 | ALOX5 (0.61) | ALOX5AKR1C3AKR1C2KMT2A | |
| SCHEMBL9707478 | 0.75 | ALOX5 (0.59) | ALOX5PTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL3151507 | 0.75 | PTGS1 (0.63) | ALOX5PTGS1PTGS2LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792560-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |