SCHEMBL2334501

SCHEMBL2334501

COc1ccc(C(C)C(=O)N(O)Cc2ccccc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 5/20 0.69
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
TDP1 Q9NUW8 2/20 0.50
PLA2G1B P04054 1/20 0.50
ATG4B Q9Y4P1 1/20 0.50
CNR2 P34972 1/20 0.50
ACHE P22303 1/20 0.50
GPR88 Q9GZN0 1/20 0.49
MAPK1 P28482 1/20 0.49
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47
PPARG P37231 1/20 0.46
PPARA Q07869 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2340070 0.83 ALOX5 (0.61) ALOX5KMT2AACHE
SCHEMBL10693720 0.82 ALOX5 (1.00) ALOX5MEN1KMT2APTGS1PTGS2
SCHEMBL6462689 0.78 ACHE (0.51) MEN1KMT2ATDP1PLA2G1BATG4B
SCHEMBL3722809 0.75 ALDH1A1 (0.56) ALOX5MEN1KMT2ATDP1ACHE
SCHEMBL17774456 0.75 ALOX5 (0.60) ALOX5MEN1KMT2APTGS1PTGS2
SCHEMBL2336992 0.74 ALOX5 (0.41) ALOX5PTGS2
SCHEMBL7040094 0.74 TDP1 (0.59) MEN1KMT2ATDP1CNR2ACHE
SCHEMBL10905939 0.73 TDP1 (0.69) MEN1KMT2ATDP1CNR2ACHE
SCHEMBL490533 0.73 NPC1 (0.52) MEN1KMT2APLA2G1BATG4BCNR2
SCHEMBL9707675 0.72 ALOX5 (0.72) ALOX5PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9210928-B2 Plant development control composition SYNGENTA CROP PROTECTION, LLC (US) 2015-12-15 US disclosed
US-20110301028-A1 PLANT DEVELOPMENT CONTROL COMPOSITION SYNGENTA CROP PROTECTION, LLC (US) 2011-12-08 US disclosed
EP-2358197-A2 PLANT DEVELOPMENT CONTROL COMPOSITION Syngenta Participations AG (CH) 2011-08-24 EP disclosed
WO-2010055316-A2 PLANT DEVELOPMENT CONTROL COMPOSITION THE UNIVERSITY OF WARWICK (GB) 2010-05-20 WO disclosed
WO-2010055310-A1 HERBICIDAL COMPOSITIONS THE UNIVERSITY OF WARWICK (GB) 2010-05-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110301028-A1 PLANT DEVELOPMENT CONTROL COMPOSITION MSL1, OXSR1, OSR1 ALOX5 3171/4885MEN1 4293/4885KMT2A 1429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.