SCHEMBL2340070

SCHEMBL2340070

COc1ccc(C(C)C(=O)N(O)Cc2ccccc2)cc1OC

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.61
HIF1A Q16665 2/20 0.52
ACHE P22303 7/20 0.49
BCHE P06276 4/20 0.49
L3MBTL1 Q9Y468 1/20 0.48
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
MAPT P10636 2/20 0.44
ALDH1A1 P00352 1/20 0.44
TAS2R14 Q9NYV8 1/20 0.44
KDM4E B2RXH2 1/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 1/20 0.44
TNF P01375 1/20 0.44
AKR1C3 P42330 1/20 0.43
AKR1C2 P52895 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2334501 0.83 ALOX5 (0.69) ALOX5ACHEKMT2A
SCHEMBL2341893 0.76 HIF1A (0.46) HIF1AACHE
SCHEMBL10693720 0.76 ALOX5 (1.00) ALOX5KMT2AAKR1C3AKR1C2
SCHEMBL490870 0.75 TTR (0.56) ALOX5HIF1AACHEL3MBTL1CA1
SCHEMBL2336706 0.75 ACHE (0.59) ALOX5ACHEBCHEL3MBTL1ALDH1A1
SCHEMBL9115746 0.74 TDP1 (0.63) ACHEBCHEL3MBTL1MAPT
SCHEMBL28219379 0.74 BCHE (0.48) ACHEBCHEL3MBTL1MAPTALDH1A1
SCHEMBL490776 0.74 ACHE (0.61) HIF1AACHEL3MBTL1CA1CA2
SCHEMBL14032691 0.74 ACHE (0.61) HIF1AACHEL3MBTL1CA1CA2
SCHEMBL5122373 0.74 ACHE (0.61) HIF1AACHEL3MBTL1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9210928-B2 Plant development control composition SYNGENTA CROP PROTECTION, LLC (US) 2015-12-15 US disclosed
US-20110301028-A1 PLANT DEVELOPMENT CONTROL COMPOSITION SYNGENTA CROP PROTECTION, LLC (US) 2011-12-08 US disclosed
EP-2358197-A2 PLANT DEVELOPMENT CONTROL COMPOSITION Syngenta Participations AG (CH) 2011-08-24 EP disclosed
WO-2010055316-A2 PLANT DEVELOPMENT CONTROL COMPOSITION THE UNIVERSITY OF WARWICK (GB) 2010-05-20 WO disclosed
WO-2010055310-A1 HERBICIDAL COMPOSITIONS THE UNIVERSITY OF WARWICK (GB) 2010-05-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110301028-A1 PLANT DEVELOPMENT CONTROL COMPOSITION MSL1, OXSR1, OSR1 ALOX5 3171/4885HIF1A 883/4885ACHE 3601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.