SCHEMBL10692733

SCHEMBL10692733

Cc1ccc(S(=O)(=O)N(CO)CO)cc1

nearest known ligand 0.63

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.59
KEAP1 Q14145 2/20 0.54
NFE2L2 Q16236 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.53
MAPT P10636 1/20 0.52
MCOLN3 Q8TDD5 1/20 0.52
CNR2 P34972 4/20 0.50
TAS2R14 Q9NYV8 2/20 0.50
C5AR1 P21730 1/20 0.48
AGER Q15109 1/20 0.48
LMNA P02545 2/20 0.48
HTT P42858 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
GAA P10253 1/20 0.48
ALDH1A1 P00352 1/20 0.48
KDM4E B2RXH2 1/20 0.48
HSD17B10 Q99714 1/20 0.48
CA12 O43570 1/20 0.47
CA9 Q16790 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL218536 0.84 SMN1; SMN2 (0.68) GLAKEAP1NFE2L2L3MBTL1MAPT
SCHEMBL8192690 0.82 SMN1; SMN2 (0.66) GLAKEAP1NFE2L2L3MBTL1MAPT
SCHEMBL15177296 0.82 SMN1; SMN2 (0.66) GLAKEAP1NFE2L2L3MBTL1MAPT
SCHEMBL7961836 0.82 KEAP1 (0.68) GLAKEAP1NFE2L2L3MBTL1CNR2
SCHEMBL11711049 0.82 SMN1; SMN2 (0.56) GLAKEAP1NFE2L2L3MBTL1MAPT
SCHEMBL10693747 0.82 MAPT (0.55) GLAKEAP1NFE2L2MAPTMCOLN3
SCHEMBL12390979 0.81 SMN1; SMN2 (0.64) GLAKEAP1NFE2L2MAPTMCOLN3
SCHEMBL1177271 0.81 GLA (0.53) GLAKEAP1NFE2L2L3MBTL1MAPT
SCHEMBL5023540 0.81 HTT (0.73) GLAL3MBTL1MAPTMCOLN3CNR2
SCHEMBL28211577 0.80 TAS2R14 (0.65) GLAMAPTMCOLN3CNR2TAS2R14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4764570-A MODIFYING MELAMINE-FORMALDEHYDE RESINS CASSELLA AKTIENGESELLSCHAFT (DE) 1988-08-16 US disclosed