Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.58 |
| ▸ | KDM4A | O75164 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | GLS | O94925 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10689564 | 0.96 | CNR1 (0.63) | CNR1KDM4AKMT2ACYP2D6CYP2C9 | |
| SCHEMBL10692448 | 0.91 | POLB (0.59) | CNR1KDM4AKMT2ACYP2D6CYP2C9 | |
| SCHEMBL10693205 | 0.82 | KLK7 (0.53) | CNR1KMT2ACYP2D6CYP2C19GLS | |
| SCHEMBL4158522 | 0.82 | PKM (0.62) | KMT2AGLSALDH1A1 | |
| SCHEMBL4162007 | 0.82 | PKM (0.62) | KMT2AGLSALDH1A1 | |
| SCHEMBL4158526 | 0.82 | PKM (0.62) | KMT2AGLSALDH1A1 | |
| SCHEMBL10693452 | 0.81 | SMN1; SMN2 (0.57) | CNR1KMT2ACNR2 | |
| SCHEMBL10694568 | 0.79 | ALDH1A1 (0.57) | KMT2AGLSALDH1A1 | |
| SCHEMBL28026853 | 0.78 | KMT2A (0.55) | CNR1KMT2AALDH1A1CNR2MAPT | |
| SCHEMBL28026850 | 0.78 | KMT2A (0.55) | CNR1KMT2AALDH1A1CNR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |