Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 12/20 | 1.00 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.56 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.51 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697496 | 0.86 | ALOX5 (1.00) | ALOX5ALDH1A1NPC1RAB9A | |
| SCHEMBL10693993 | 0.84 | ALOX5 (1.00) | ALOX5LTB4RLTB4R2 | |
| SCHEMBL11574138 | 0.79 | ALOX5 (0.65) | ALOX5LTB4RLTB4R2ALDH1A1NPC1 | |
| SCHEMBL10692128 | 0.79 | ALOX5 (0.88) | ALOX5LTB4RLTB4R2 | |
| SCHEMBL10695836 | 0.79 | ALOX5 (0.88) | ALOX5LTB4RLTB4R2 | |
| SCHEMBL10692771 | 0.77 | ALOX5 (1.00) | ALOX5LTB4RLTB4R2 | |
| SCHEMBL27882351 | 0.77 | ALOX5 (0.63) | ALOX5ALDH1A1NPC1RAB9ALPAR1 | |
| SCHEMBL4032340 | 0.76 | NPC1 (0.66) | ALOX5ALDH1A1NPC1RAB9A | |
| SCHEMBL28267555 | 0.76 | TDP1 (0.69) | ALOX5ALDH1A1NPC1RAB9A | |
| SCHEMBL341939 | 0.76 | ALOX5 (0.60) | ALOX5LTB4RLTB4R2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | claimed |
| US-4792560-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | disclosed |