Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25249974 | 0.76 | ALDH1A1 (0.44) | ALDH1A1HSD17B10TDP1MAPTNPSR1 | |
| SCHEMBL1940334 | 0.76 | TP53 (0.41) | ALDH1A1HSD17B10MAPTNPSR1NPC1 | |
| SCHEMBL765855 | 0.73 | APLNR (0.41) | ALDH1A1HSD17B10MAPTNPSR1NPC1 | |
| SCHEMBL16969 | 0.73 | ALDH1A1 (0.46) | ALDH1A1HSD17B10TDP1MAPTNPSR1 | |
| SCHEMBL31190821 | 0.72 | ALDH1A1 (0.37) | ALDH1A1HSD17B10TDP1 | |
| SCHEMBL23043606 | 0.72 | ALDH1A1 (0.41) | ALDH1A1HSD17B10TDP1MAPTSMN1; SMN2 | |
| SCHEMBL13241046 | 0.71 | ALDH1A1 (0.44) | ALDH1A1HSD17B10TDP1MAPTLMNA | |
| SCHEMBL27285665 | 0.71 | ALDH1A1 (0.44) | ALDH1A1HSD17B10TDP1 | |
| SCHEMBL2768266 | 0.71 | ALDH1A1 (0.44) | ALDH1A1HSD17B10TDP1TP53LMNA | |
| SCHEMBL66565 | 0.71 | KDM4E (0.35) | ALDH1A1HSD17B10MAPTNPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255890-A1 | Process for the reaction of amines with heterocyclic reactive compounds | BAYER AG (DE) | 1988-02-17 | — | — | EP | disclosed |