Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10977746 | 0.79 | NFE2L2 (0.38) | ALDH1A1HTTMAPK1NFE2L2LMNA | |
| SCHEMBL765855 | 0.77 | APLNR (0.41) | TP53MAPTTLR9NPC1ALDH1A1 | |
| SCHEMBL10694027 | 0.76 | ALDH1A1 (0.41) | TP53MAPTTLR9NPC1ALDH1A1 | |
| SCHEMBL3210214 | 0.75 | CA12 (0.40) | TP53MAPTTLR9NPC1ALDH1A1 | |
| SCHEMBL28832576 | 0.75 | LMNA (0.35) | TP53MAPTTLR9NPC1ALDH1A1 | |
| SCHEMBL7043547 | 0.75 | APLNR (0.41) | TP53MAPTTLR9NPC1ALDH1A1 | |
| SCHEMBL66565 | 0.75 | KDM4E (0.35) | TP53MAPTTLR9NPC1ALDH1A1 | |
| SCHEMBL27371612 | 0.75 | NPC1 (0.38) | TP53MAPTTLR9NPC1ALDH1A1 | |
| SCHEMBL7586541 | 0.73 | MAPT (0.55) | TP53MAPTTLR9NPC1ALDH1A1 | |
| SCHEMBL3631289 | 0.73 | MAPT (0.51) | TP53MAPTTLR9NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033195-B1 | PYRIMIDINE-2-SULPHIDES AND THEIR S-OXIDES FOR USE IN MEDICINE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, PROCESSES FOR THEIR PREPARATION AND SUCH COMPOUNDS WHEN NOVEL PER SE | NYEGAARD & CO. A/S (NO) | 1985-12-04 | — | — | EP | claimed |
| US-4423047-A | INHIBITING ABNORMAL CELL PROLIFERATION | NYEGAARD & CO. A/S (NO) | 1983-12-27 | — | — | US | claimed |
| EP-0033195-A1 | Pyrimidine-2-sulphides and their S-oxides for use in medicine, pharmaceutical compositions containing them, processes for their preparation and such compounds when novel per se | NYEGAARD & CO. A/S (NO) | 1981-08-05 | — | — | EP | claimed |
| CN-122039076-A | Preparation method of 2-methyl sulfoxide pyrimidine derivative | 石河子大学 | 2026-05-15 | — | — | CN | disclosed |
| EP-4069680-B1 | PROCESS FOR SYNTHESIS OF A 2-(5-ISOXAZOLYL)-PHENOL | FMC CORP (US) | 2026-03-25 | — | — | EP | disclosed |
| US-12516045-B2 | Process for synthesis of a 2-thioalkyl pyrimidine | FMC CORPORATION (US) | 2026-01-06 | — | — | US | disclosed |
| US-20250179051-A1 | PYRIMIDINLY-OXY-QUINOLINE BASED HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-06-05 | — | — | US | disclosed |
| US-20250179052-A1 | PYRIMIDINYL-OXY-QUINOLINE BASED HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-06-05 | — | — | US | disclosed |
| US-12291525-B2 | Process for synthesis of a 2-(5-isoxazolyl)-phenol | FMC CORPORATION (US) | 2025-05-06 | — | — | US | disclosed |
| CN-111574510-B | Pyrimidine as herbicide Oxyphenyl derivatives | FMC 公司 | 2025-03-07 | — | — | CN | disclosed |
| EP-4486736-A1 | PYRIMIDINYL-OXY-QUINOLINE BASED HERBICIDAL COMPOUNDS | Syngenta Crop Protection AG (CH) | 2025-01-08 | — | — | EP | disclosed |
| EP-0058173-A4 | PROCESS FOR THE SYNTHESIS OF ARYLOXY DERIVATIVES. | ICI AUSTRALIA LTD (AU) | 1982-12-27 | — | — | EP | disclosed |
| EP-0013936-B1 | REACTIVE AZO DYESTUFFS, THEIR PREPARATION AND THEIR USE IN DYEING MATERIALS CONTAINING HYDROXYL GROUPS AND AMIDE GROUPS | BAYER AG (DE) | 1982-09-22 | — | — | EP | disclosed |
| EP-0058173-A1 | PROCESS FOR THE SYNTHESIS OF ARYLOXY DERIVATIVES. | ICI AUSTRALIA LTD (AU) | 1982-08-25 | — | — | EP | disclosed |
| WO-1982000638-A1 | PROCESS FOR THE SYNTHESIS OF ARYLOXY DERIVATIVES | WATSON K | 1982-03-04 | — | — | WO | disclosed |
| EP-0033195-A1 | Pyrimidine-2-sulphides and their S-oxides for use in medicine, pharmaceutical compositions containing them, processes for their preparation and such compounds when novel per se | NYEGAARD & CO. A/S (NO) | 1981-08-05 | — | — | EP | disclosed |
| US-4248618-A | Derivatives of (pyrimidyloxy)phenoxy-alkanecarboxylic acid and herbicidal compositions thereof | ICI AUSTRALIA LIMITED (AU) | 1981-02-03 | — | — | US | disclosed |
| US-4248619-A | Bis[pyrimidyloxy(thio)]benzene derivatives | ICI AUSTRALIA LIMITED (AU) | 1981-02-03 | — | — | US | disclosed |
| EP-0015124-A1 | Parasiticidal heterocyclic ether derivatives, processes for the manufacture thereof and compositions thereof | ICI AUSTRALIA LIMITED (AU) | 1980-09-03 | — | — | EP | disclosed |
| EP-0008192-A1 | Bis(pyrimidyloxy)-, bis(pyrimidylthio)-, and pyrimidyloxy-pyrimidylthio-benzene derivatives and their use as herbicides, and processes of preparing them | ICI AUSTRALIA LIMITED (AU) | 1980-02-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12291525-B2 | Process for synthesis of a 2-(5-isoxazolyl)-phenol | CYP4F11, CYP2F1, CYP1A2 | TP53 2903/4885MAPT 4326/4885TLR9 3636/4885 |
| US-20250179052-A1 | PYRIMIDINYL-OXY-QUINOLINE BASED HERBICIDAL COMPOUNDS | PRXL2A, QDPR, PRDX1 | TP53 3549/4885MAPT 4441/4885TLR9 2869/4885 |
| US-20250179051-A1 | PYRIMIDINLY-OXY-QUINOLINE BASED HERBICIDAL COMPOUNDS | PRXL2A, PRDX1, PRDX2 | TP53 3753/4885MAPT 4462/4885TLR9 2586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.