Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 3/20 | 0.33 |
| ▸ | S100A4 | P26447 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CASP4 | P49662 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | CASP9 | P55211 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696788 | 0.81 | — | — | |
| SCHEMBL10697215 | 0.81 | S100A4 (0.34) | S100A4NR1H2NR1H3 | |
| SCHEMBL8085297 | 0.80 | MAPT (0.35) | ALDH1A1CA9CA1CA2CA7 | |
| SCHEMBL9371977 | 0.80 | CA1 (0.35) | ALDH1A1CA9CA1CA2CA7 | |
| SCHEMBL10694946 | 0.80 | PDE4A (0.41) | CASP3MALT1 | |
| SCHEMBL10698039 | 0.79 | CA9 (0.36) | ALDH1A1CA9CA1CA2CA7 | |
| SCHEMBL10697118 | 0.79 | RAB9A (0.37) | ALDH1A1CA9CA1CA2CA7 | |
| SCHEMBL8085035 | 0.78 | ALDH1A1 (0.38) | ALDH1A1CA9CA1CA2CA7 | |
| SCHEMBL10433223 | 0.78 | ALDH1A1 (0.36) | ALDH1A1CA9CA1CA2CA7 | |
| SCHEMBL7377496 | 0.77 | CCNC (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273262-A2 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1988-07-06 | — | — | EP | disclosed |