Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697118 | 0.88 | RAB9A (0.37) | RARARARBRARGPDK2 | |
| SCHEMBL10696972 | 0.87 | RARA (0.31) | RARARARBRARG | |
| SCHEMBL10693640 | 0.86 | MAPT (0.41) | RARARARB | |
| SCHEMBL10696788 | 0.82 | — | — | |
| SCHEMBL10694946 | 0.81 | PDE4A (0.41) | KDM4E | |
| SCHEMBL10694147 | 0.81 | ALDH1A1 (0.36) | S100A4NR1H2NR1H3 | |
| SCHEMBL8084539 | 0.80 | S100A4 (0.32) | S100A4KDM4E | |
| SCHEMBL7377496 | 0.78 | CCNC (0.30) | — | |
| SCHEMBL7277136 | 0.77 | S100A4 (0.38) | S100A4RARARARBRARGKDM4E | |
| SCHEMBL10697122 | 0.76 | MAPT (0.34) | S100A4RARARARBRARGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273262-A2 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1988-07-06 | — | — | EP | disclosed |