Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770716 | 0.83 | PARP1 (0.44) | PDE10AELANEPARP1MAPTPOLB | |
| SCHEMBL9533212 | 0.82 | PARP1 (0.40) | PDE10AELANEPARP1MAPTPOLB | |
| SCHEMBL9770643 | 0.80 | ELANE (0.39) | PDE10AELANEPARP1MAPTPOLB | |
| SCHEMBL10696374 | 0.79 | KDM4E (0.49) | MAPTPOLBRXFP1NPC1DUSP3 | |
| SCHEMBL9535344 | 0.77 | ELANE (0.43) | ELANEMAPTAPPHRH3KCNH2 | |
| SCHEMBL10694401 | 0.73 | ELANE (0.47) | ELANEMAPTPOLBHRH3KCNH2 | |
| SCHEMBL9536653 | 0.72 | ELANE (0.40) | ELANEPARP1MAPTPIK3CDNPC1 | |
| SCHEMBL18701129 | 0.72 | MAPT (0.41) | MAPTF2RL3 | |
| SCHEMBL9534833 | 0.71 | CYP1A2 (0.50) | ELANEPARP1MAPTNPC1 | |
| SCHEMBL10695492 | 0.70 | PARP1 (0.39) | ELANEPARP1MAPTRXFP1F2RL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |