SCHEMBL10694425

SCHEMBL10694425

N#Cc1[nH]c(-c2ccccc2F)nc1C(N)=O

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 5/20 0.54
SLC9A1 P19634 4/20 0.52
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
ALDH1A1 P00352 1/20 0.42
PKM P14618 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CDC7 O00311 1/20 0.38
MGAM O43451 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
DHODH Q02127 1/20 0.37
DCUN1D1 Q96GG9 1/20 0.37
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
GRM2 Q14416 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Valine SCHEMBL10695541 0.88 SLC9A1 (0.45) PARP1SLC9A1NPC1RAB9AALDH1A1
SCHEMBL10695611 0.84 PARP1 (0.54) PARP1SLC9A1NPC1RAB9AALDH1A1
SCHEMBL10694398 0.84 SLC9A1 (0.54) PARP1SLC9A1NPC1RAB9AALDH1A1
SCHEMBL10695586 0.83 PARP1 (0.57) PARP1SLC9A1CDC7
SCHEMBL11470139 0.80 SLC9A1 (0.56) PARP1SLC9A1NPC1RAB9AALDH1A1
SCHEMBL10695803 0.78 CHEK2 (0.47) PARP1NPC1RAB9AALDH1A1
SCHEMBL10697442 0.77 ALDH1A1 (0.49) PARP1NPC1RAB9AALDH1A1PKM
SCHEMBL10697513 0.76 PIN1 (0.55) PARP1SLC9A1CDC7MGAMGAA
SCHEMBL10697288 0.74 MEN1 (0.48) PARP1SLC9A1CDC7GAA
SCHEMBL10694134 0.73 PARP1 (0.50) PARP1NPC1RAB9AALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0269238-A1 Imidazoles and their compositions for plant growth regulation MAY & BAKER LIMITED (GB) 1988-06-01 EP disclosed