Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | LGMN | Q99538 | 1/20 | 0.36 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694425 | 0.83 | PARP1 (0.54) | PARP1CDC7SLC9A1 | |
| SCHEMBL10694398 | 0.81 | SLC9A1 (0.54) | PARP1SLC9A1 | |
| SCHEMBL10695611 | 0.81 | PARP1 (0.54) | PARP1SLC9A1 | |
| SCHEMBL10695343 | 0.79 | PARP1 (0.45) | PARP1HDAC3HDAC7HDAC10HDAC6 | |
| SCHEMBL10694101 | 0.77 | PARP1 (0.54) | PARP1 | |
| Valine SCHEMBL10695541 | 0.73 | SLC9A1 (0.45) | PARP1SLC9A1LGMN | |
| SCHEMBL7320347 | 0.72 | PARP1 (1.00) | PARP1 | |
| SCHEMBL10695803 | 0.72 | CHEK2 (0.47) | PARP1HDAC3HDAC6 | |
| SCHEMBL9220531 | 0.72 | NPBWR1 (0.36) | PARP1 | |
| SCHEMBL10694053 | 0.72 | CHEK2 (0.48) | PARP1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269238-A1 | Imidazoles and their compositions for plant growth regulation | MAY & BAKER LIMITED (GB) | 1988-06-01 | — | — | EP | disclosed |