Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 8/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.52 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.50 |
| ▸ | CBFB | Q13951 | 1/20 | 0.50 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694441 | 0.88 | KDM4E (0.65) | NPBWR1KCNH2DGAT1ALDH1A1CYP1A2 | |
| SCHEMBL2361268 | 0.87 | NPSR1 (0.46) | NPBWR1KCNH2DGAT1ALDH1A1CYP1A2 | |
| SCHEMBL14336639 | 0.83 | KCNH2 (0.62) | NPBWR1KCNH2DGAT1ALDH1A1CYP1A2 | |
| SCHEMBL1311258 | 0.79 | NPBWR1 (0.58) | NPBWR1KCNH2DGAT1SCN10ADYRK1A | |
| SCHEMBL1835419 | 0.79 | ALPL (0.51) | KCNH2ALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL20494892 | 0.78 | DGAT1 (0.42) | NPBWR1KCNH2DGAT1ALDH1A1CYP1A2 | |
| SCHEMBL1358510 | 0.77 | ALDH1A1 (0.58) | ALDH1A1CYP1A2CYP2C9HPGDCYP2C19 | |
| SCHEMBL31267625 | 0.76 | ALDH1A1 (0.51) | KCNH2ALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL17690481 | 0.76 | ALDH1A1 (0.42) | KCNH2DGAT1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL30672494 | 0.76 | NPBWR1 (0.58) | NPBWR1KCNH2DGAT1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150289512-A1 | METHOD FOR PROMOTING PLANT GROWTH | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-10-15 | — | — | US | disclosed |
| US-7544803-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2009-06-09 | — | — | US | disclosed |
| US-7544803-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2009-06-09 | — | — | US | disclosed |
| US-7544803-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2009-06-09 | — | — | US | disclosed |
| US-20050165049-A1 | Vanilloid receptor ligands and their use in treatments | AMGEN, INC. | 2005-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165049-A1 | Vanilloid receptor ligands and their use in treatments | TRPV1, TRPV2, TRPV3 | NPBWR1 364/4885KCNH2 384/4885DGAT1 2203/4885 |
| US-20150289512-A1 | METHOD FOR PROMOTING PLANT GROWTH | FGF1, MKI67, FGF2 | NPBWR1 753/4885KCNH2 3941/4885DGAT1 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.