Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 9/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL6705370 | 0.99 | NR3C1 (0.34) | ALDH1A1NR3C1PGRNR3C2AR | |
| SCHEMBL8746609 | 0.96 | ALDH1A1 (0.36) | ALDH1A1NR3C1PGRNR3C2AR | |
| Sulfuric Acid SCHEMBL7553547 | 0.87 | POLB (0.38) | ALDH1A1NR3C1PGRNR3C2AR | |
| Sulfuric Acid SCHEMBL9555436 | 0.84 | CD44 (0.38) | ALDH1A1ESR1 | |
| Sulfuric Acid SCHEMBL9680107 | 0.83 | MEN1 (0.38) | ALDH1A1ESR1 | |
| SCHEMBL10381631 | 0.83 | POLB (0.41) | ALDH1A1NR3C1PGRNR3C2AR | |
| Sulfuric Acid SCHEMBL5699530 | 0.80 | GAA (0.37) | ALDH1A1 | |
| SCHEMBL15894608 | 0.79 | POLB (0.40) | ALDH1A1NR3C1PGRNR3C2AR | |
| SCHEMBL6665267 | 0.78 | MTNR1A (0.42) | ALDH1A1 | |
| Sulfuric Acid SCHEMBL27602600 | 0.78 | NR3C1 (0.34) | ALDH1A1NR3C1PGRNR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041438-B1 | Silver halide photographic light-sensitive material, heterocyclic azo dye forming compound, and method of preparing dye | FUJI PHOTO FILM CO LTD (JP) | 2006-06-14 | — | — | EP | disclosed |
| EP-0621507-B1 | Colour development composition and processing method using composition | CHUGAI SHASHIN YAKUHIN (JP) | 1997-10-08 | — | — | EP | disclosed |
| EP-0567126-A1 | Processing composition for silver halide photographic material and processing method using same | FUJI PHOTO FILM CO., LTD. (JP) | 1993-10-27 | — | — | EP | disclosed |
| EP-0294149-B1 | SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL AND PROCESSING METHOD THEREFORE | KONICA CORPORATION (JP) | 1993-09-01 | — | — | EP | disclosed |
| EP-0273429-B1 | CORNER DEVELOPMENT TYPE SILVER HALIDE PHOTOGRAPHIC EMULSIONS | FUJI PHOTO FILM CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |
| EP-0422513-A2 | A silver halide photographic light-sensitive material containing a novel yellow coupler | KONICA CORPORATION (JP) | 1991-04-17 | — | — | EP | disclosed |
| EP-0294149-A2 | Silver halide photographic light-sensitive material and processing method therefore | KONICA CORPORATION (JP) | 1988-12-07 | — | — | EP | disclosed |