Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694640 | 0.78 | ALDH1A1 (0.44) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL29187823 | 0.73 | NOTUM (0.47) | ALDH1A1NOTUMLMNAPOLBMEN1 | |
| SCHEMBL10507943 | 0.69 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2SIGMAR1 | |
| SCHEMBL10689221 | 0.68 | NOTUM (0.41) | ALDH1A1NOTUMLMNAPOLBMEN1 | |
| SCHEMBL10508879 | 0.64 | ADRA1D (0.49) | SIGMAR1 | |
| N-Benzylmethylamine SCHEMBL432493 | 0.64 | MAPT (0.74) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL30573244 | 0.63 | NOTUM (0.53) | NOTUMLMNAPOLBMEN1KMT2A | |
| N-Benzylmethylamine SCHEMBL28296920 | 0.62 | MAPT (0.77) | ALDH1A1LMNATSHRMEN1KMT2A | |
| N-Benzylmethylamine SCHEMBL7691663 | 0.61 | CYP3A4 (0.68) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| N-Benzylmethylamine SCHEMBL27884857 | 0.61 | KDM4E (0.74) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792559-A | 1,2,3,4-tetrahydroquinoline substituted 5-aminopentanenitrile compounds and their use as calcium modulators | ADIR ET COMPAGNIE (FR) | 1988-12-20 | — | — | US | disclosed |