Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.53 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | PLK4 | O00444 | 1/20 | 0.51 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.51 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | PRKCG | P05129 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690915 | 0.84 | MEN1 (0.54) | ALDH1A1KMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL19273224 | 0.83 | ALDH1A1 (0.55) | ALDH1A1RAB9APOLBNPC1MAOB | |
| SCHEMBL19273221 | 0.83 | ALDH1A1 (0.55) | ALDH1A1RAB9APOLBNPC1MAOB | |
| SCHEMBL10690147 | 0.81 | NPC1 (0.59) | ALDH1A1RAB9ANPC1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL9473351 | 0.80 | ALDH1A1 (0.55) | ALDH1A1RAB9ALMNASMN1; SMN2RPS6KA5 | |
| SCHEMBL10692204 | 0.77 | ALDH1A1 (0.49) | ALDH1A1RAB9APOLBNPC1MAOB | |
| SCHEMBL20911008 | 0.76 | RAB9A (0.75) | ALDH1A1RAB9APOLBNPC1MAOB | |
| SCHEMBL4963071 | 0.75 | LMNA (0.56) | ALDH1A1RAB9APOLBNPC1MAOB | |
| SCHEMBL1709292 | 0.75 | HPGD (0.65) | ALDH1A1RAB9APOLBNPC1MAOB | |
| SCHEMBL744864 | 0.75 | NPC1 (0.59) | ALDH1A1RAB9ANPC1MAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | claimed |