Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691473 | 0.90 | RIPK1 (0.53) | ALDH1A1HPGDRAB9ALMNASMN1; SMN2 | |
| SCHEMBL10694465 | 0.88 | SMN1; SMN2 (0.54) | ALDH1A1HPGDKDM4ERAB9ANPC1 | |
| SCHEMBL10692252 | 0.87 | MEN1 (0.46) | ALDH1A1HPGDPOLBKMT2ACYP1A2 | |
| SCHEMBL10693154 | 0.86 | NPC1 (0.54) | ALDH1A1HPGDRAB9ANPC1POLB | |
| SCHEMBL19273221 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4ERAB9ANPC1 | |
| SCHEMBL19273224 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4ERAB9ANPC1 | |
| SCHEMBL10694507 | 0.79 | CNR1 (0.40) | ALDH1A1RAB9ANPC1KMT2ACYP2C19 | |
| SCHEMBL10694723 | 0.77 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4ERAB9ANPC1 | |
| SCHEMBL9501899 | 0.77 | MMP8 (0.50) | ALDH1A1HPGDRAB9ANPC1POLB | |
| SCHEMBL10692779 | 0.75 | POLB (0.61) | HPGDKDM4ERAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |