Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.44 |
| ▸ | TYMP | P19971 | 1/20 | 0.43 |
| ▸ | TYMS | P04818 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693954 | 1.00 | TK1 (0.47) | TK1BCHETYMPTYMSHSP90AA1 | |
| SCHEMBL10483794 | 0.90 | TK1 (0.48) | TK1BCHETYMPTYMSHSP90AA1 | |
| SCHEMBL10483796 | 0.90 | TK1 (0.48) | TK1BCHETYMPTYMSHSP90AA1 | |
| SCHEMBL9100246 | 0.89 | HSP90AA1 (0.54) | TK1TYMPTYMSHSP90AA1RNASE1 | |
| SCHEMBL10694464 | 0.89 | TYMS (0.44) | TK1TYMPTYMSHSP90AA1RNASE1 | |
| SCHEMBL9100241 | 0.89 | HSP90AA1 (0.54) | TK1TYMPTYMSHSP90AA1RNASE1 | |
| SCHEMBL10694460 | 0.89 | TYMS (0.44) | TK1TYMPTYMSHSP90AA1RNASE1 | |
| SCHEMBL9780827 | 0.88 | TK1 (0.44) | TK1TYMPTYMSRNASE1 | |
| SCHEMBL9780832 | 0.88 | TK1 (0.44) | TK1TYMPTYMSRNASE1 | |
| SCHEMBL10693997 | 0.88 | LMNA (0.50) | TK1TYMPTYMSHSP90AA1RNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252989-A1 | 2'-DEOXY-5-TRIFLUOROMETHYLURIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1988-01-20 | — | — | EP | disclosed |