Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TYMS | P04818 | 4/20 | 0.45 |
| ▸ | TYMP | P19971 | 1/20 | 0.43 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.41 |
| ▸ | TK1 | P04183 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9100241 | 1.00 | HSP90AA1 (0.54) | HSP90AA1LMNASMN1; SMN2TYMSTYMP | |
| SCHEMBL10693997 | 0.89 | LMNA (0.50) | HSP90AA1LMNASMN1; SMN2TYMSTYMP | |
| SCHEMBL10692453 | 0.89 | LMNA (0.50) | HSP90AA1LMNASMN1; SMN2TYMSTYMP | |
| SCHEMBL10694460 | 0.89 | TYMS (0.44) | HSP90AA1SMN1; SMN2TYMSTYMPRNASE1 | |
| SCHEMBL10694464 | 0.89 | TYMS (0.44) | HSP90AA1SMN1; SMN2TYMSTYMPRNASE1 | |
| SCHEMBL10694863 | 0.89 | TK1 (0.47) | HSP90AA1TYMSTYMPRNASE1TK1 | |
| SCHEMBL10693954 | 0.89 | TK1 (0.47) | HSP90AA1TYMSTYMPRNASE1TK1 | |
| SCHEMBL9780832 | 0.88 | TK1 (0.44) | TYMSTYMPRNASE1TK1 | |
| SCHEMBL9780827 | 0.88 | TK1 (0.44) | TYMSTYMPRNASE1TK1 | |
| SCHEMBL9098705 | 0.85 | HSP90AA1 (0.51) | HSP90AA1LMNASMN1; SMN2TYMSTYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323441-B1 | 5-Fluorouracil derivatives | OTSUKA PHARMA CO LTD (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5155113-A | Administering 5-fluorouracil and derivatives with pyridine and pyridone derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0180188-B1 | A COMPOSITION FOR INCREASING THE ANTI-CANCER ACTIVITY OF AN ANTI-CANCER COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-15 | — | — | EP | disclosed |
| US-4983609-A | Anticancer agents | OTSUKA PHARMACEUTICAL (JP) | 1991-01-08 | — | — | US | disclosed |
| US-4864021-A | ANTICARCINOGENIC AGENTS, ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0323441-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |
| EP-0180897-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-14 | — | — | EP | disclosed |
| EP-0180188-A2 | A composition for increasing the anti-cancer activity of an anti-cancer compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-07 | — | — | EP | disclosed |