Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ATP4A | P20648 | 3/20 | 0.45 |
| ▸ | ATP4B | P51164 | 3/20 | 0.45 |
| ▸ | BRD4 | O60885 | 4/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2189993 | 0.83 | ATP4A (0.60) | MAPK1MAPTTDP1L3MBTL1ATP4A | |
| SCHEMBL10916933 | 0.74 | ATP4A (0.57) | L3MBTL1ATP4AATP4BBRD4ADORA3 | |
| SCHEMBL11097237 | 0.73 | ATP4A (0.49) | MAPK1MAPTTDP1L3MBTL1ATP4A | |
| SCHEMBL2191140 | 0.73 | MEN1 (0.51) | MAPK1MAPTATP4AATP4BMEN1 | |
| SCHEMBL10686609 | 0.72 | ATP4A (0.74) | MAPK1MAPTTDP1L3MBTL1ATP4A | |
| SCHEMBL10689756 | 0.72 | ATP4A (0.55) | MAPK1MAPTTDP1L3MBTL1ATP4A | |
| SCHEMBL5423755 | 0.72 | GCK (0.46) | MAPK1MAPTTDP1L3MBTL1ATP4A | |
| SCHEMBL5619637 | 0.72 | GCK (0.46) | MAPK1MAPTTDP1L3MBTL1ATP4A | |
| SCHEMBL2194287 | 0.72 | PPARG (0.50) | MAPK1MAPTL3MBTL1ATP4AATP4B | |
| SCHEMBL9746834 | 0.72 | PPARG (0.50) | MAPTATP4AATP4BADORA3ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738967-A | Imidazoisoquinoline compounds useful as anti-ulcerative agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| US-4686227-A | Imidazoisoquinoline compounds useful as anti-ulcerative agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-08-11 | — | — | US | disclosed |
| EP-0165545-A2 | Imidazoisoquinoline compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-12-27 | — | — | EP | disclosed |