Triethylene Glycol

Triethylene Glycol

SCHEMBL10695052

Cc1ccc(CS(N)(=O)=O)cc1.OCCOCCOCCO

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 8/20 0.45
CA2 P00918 8/20 0.45
CA9 Q16790 8/20 0.45
CA5A P35218 4/20 0.43
KMT2A Q03164 4/20 0.41
ALDH1A1 P00352 2/20 0.38
KIF11 P52732 1/20 0.38
CYP2C19 P33261 1/20 0.36
MEN1 O00255 2/20 0.36
USP2 O75604 1/20 0.36
LMNA P02545 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPK1 P28482 1/20 0.36
CASP1 P29466 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
SLCO1B3 Q9NPD5 1/20 0.36
SLCO1B1 Q9Y6L6 1/20 0.36
CA12 O43570 3/20 0.36
CA7 P43166 3/20 0.36
CA6 P23280 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3229364 0.82 CA1 (0.60) CA1CA2CA9CA5AKMT2A
SCHEMBL4057569 0.80 CA1 (0.58) CA1CA2CA9CA5AKMT2A
P-Xylene SCHEMBL18334385 0.76 TSHR (0.56) KMT2AALDH1A1MEN1USP2LMNA
P-Xylene SCHEMBL27968200 0.76 TSHR (0.56) KMT2AALDH1A1MEN1USP2LMNA
SCHEMBL16682541 0.75 AGXT (0.47) CA1CA2CA9KMT2AALDH1A1
SCHEMBL16449107 0.75 AGXT (0.47) CA1CA2CA9KMT2AALDH1A1
Tetraethylene Glycol SCHEMBL1145155 0.75 ALDH1A1 (0.49) CA1CA2CA9CA5AKMT2A
Hexaethylene Glycol SCHEMBL4379136 0.75 ALDH1A1 (0.49) CA1CA2CA9CA5AKMT2A
Tetraethylene Glycol SCHEMBL3062384 0.75 ALDH1A1 (0.49) CA1CA2CA9CA5AKMT2A
Triethylene Glycol SCHEMBL6130636 0.75 ALDH1A1 (0.49) CA1CA2CA9CA5AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4764570-A MODIFYING MELAMINE-FORMALDEHYDE RESINS CASSELLA AKTIENGESELLSCHAFT (DE) 1988-08-16 US disclosed