Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hexaethylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137364 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP1A2SMN1; SMN2LMNA | |
| SCHEMBL29249377 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP1A2SMN1; SMN2LMNA | |
| SCHEMBL28704841 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP1A2SMN1; SMN2LMNA | |
| SCHEMBL28618062 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP1A2SMN1; SMN2LMNA | |
| Pentaethylene Glycol SCHEMBL3466434 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP1A2SMN1; SMN2LMNA | |
| Hexaethylene Glycol SCHEMBL11280667 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP1A2SMN1; SMN2LMNA | |
| Tetraethylene Glycol SCHEMBL1145155 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP1A2SMN1; SMN2LMNA | |
| Tetraethylene Glycol SCHEMBL3062384 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP1A2SMN1; SMN2LMNA | |
| Triethylene Glycol SCHEMBL6130636 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP1A2SMN1; SMN2LMNA | |
| SCHEMBL27633211 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP1A2SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122012012-A | High-strength low-temperature-resistant recyclable adhesive and preparation method thereof | 四川大学 | 2026-05-12 | — | — | CN | claimed |
| CN-122012012-A | High-strength low-temperature-resistant recyclable adhesive and preparation method thereof | 四川大学 | 2026-05-12 | — | — | CN | disclosed |
| EP-4652160-A1 | COMPOUNDS FOR NUCLEIC ACID CLEAVAGE | Cambridge Enterprise Limited (GB) | 2025-11-26 | — | — | EP | disclosed |
| US-20250332318-A1 | POLYMER PARTICLES | TERUMO CORP (JP) | 2025-10-30 | — | — | US | disclosed |
| US-12364786-B2 | Polymer particles | TERUMO CORPORATION (JP) | 2025-07-22 | — | — | US | disclosed |
| US-20240417778-A1 | Methods for Nucleic Acid Cleavage | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2024-12-19 | — | — | US | disclosed |
| EP-4423295-A2 | METHODS FOR NUCLEIC ACID CLEAVAGE | Cambridge Enterprise Limited (GB) | 2024-09-04 | — | — | EP | disclosed |
| WO-2024153950-A1 | COMPOUNDS FOR NUCLEIC ACID CLEAVAGE | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2024-07-25 | — | — | WO | disclosed |
| WO-2024153952-A1 | COMPOUNDS FOR NUCLEIC ACID CLEAVAGE | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2024-07-25 | — | — | WO | disclosed |
| EP-3518994-B1 | POLYMER PARTICLES | TERUMO CORP (JP) | 2024-02-07 | — | — | EP | disclosed |
| WO-2021078301-A1 | PROTEIN DEGRADING AGENT AND USE THEREOF IN TREATMENT OF DISEASES | 上海科技大学 | 2021-04-29 | — | — | WO | disclosed |
| US-20200255689-A1 | POLISHING COMPOSITION AND METHOD OF FABRICATING SEMICONDUCTOR DEVICE USING THE SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2020-08-13 | — | — | US | disclosed |
| US-20200215222-A1 | POLYMER PARTICLES | MICROVENTION, INC. | 2020-07-09 | — | — | US | disclosed |
| US-10201632-B2 | Polymer particles | TERUMO CORPORATION (JP) | 2019-02-12 | — | — | US | disclosed |
| US-20180085497-A1 | POLYMER PARTICLES | TERUMO CORPORATION (JP) | 2018-03-29 | — | — | US | disclosed |
| US-8436197-B2 | Palladium complexes and polymerization and coupling processes thereof | WEST CHESTER UNIVERSITY OF PENNSYLVANIA OF THE STATE SYSTEM OF HIGHER EDUCATION (US) | 2013-05-07 | — | — | US | disclosed |
| US-20090111962-A1 | Palladium Complexes and Polymerization and Coupling Processes Thereof | WEST CHESTER UNIVERSITY OF PENNSYLVANIA OF THE STATE SYSTEM OF HIGHER EDUCATION | 2009-04-30 | — | — | US | disclosed |
| US-6441164-B2 | A CROWN ETHER SUBSTITUTED BY EITHER ONE OR BOTH OF THE NITROGEN OF AN N,N'-DI-C1-C4-ALKYL-P-PHENYLENEDIAMINE; REDOX ACTIVE; BINDING METALS AND METAL IONS; DETECTORS; CHARGE TRANSFER COMPOUNDS; SWITCHES; MRI CONTRAST AGENTS | EAST CAROLINA UNIVERSITY | 2002-08-27 | — | — | US | disclosed |
| US-20010047095-A1 | A crown ether substituted by either one or both of the nitrogen of an N,N'-di-C1-C4-alkyl-p-phenylenediamine; redox active; binding metals and metal ions; detectors; charge transfer compounds; switches; MRI contrast agents | SIBERT JOHN W (US) | 2001-11-29 | — | — | US | disclosed |
| US-6262258-B1 | UEFUL AS REDOX SWITCHES, SENSORS, TRANSPORT AGENTS, AND ELECTROCATALYSTS | EAST CAROLINA UNIVERSITY | 2001-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200215222-A1 | POLYMER PARTICLES | FGB, PLG, PLAT | ALDH1A1 3057/4885CYP2C9 3457/4885CYP1A2 3886/4885 |
| US-20250332318-A1 | POLYMER PARTICLES | FGB, PLG, PLAT | ALDH1A1 3057/4885CYP2C9 3457/4885CYP1A2 3886/4885 |
| US-12364786-B2 | Polymer particles | FGB, PLG, PLAT | ALDH1A1 3057/4885CYP2C9 3457/4885CYP1A2 3886/4885 |
| US-20090111962-A1 | Palladium Complexes and Polymerization and Coupling Processes Thereof | DDT, PDCD2L, PDCD1LG2 | ALDH1A1 1671/4885CYP2C9 2211/4885CYP1A2 3534/4885 |
| US-10201632-B2 | Polymer particles | FGB, PLG, PLAT | ALDH1A1 3057/4885CYP2C9 3457/4885CYP1A2 3886/4885 |
| US-20010047095-A1 | A crown ether substituted by either one or both of the nitrogen of an N,N'-di-C1-C4-alkyl-p-phenylenediamine; redox active; binding metals and metal ions; detectors; charge transfer compounds; switches; MRI contrast agents | CBR3, CBR1, AOC3 | ALDH1A1 3095/4885CYP2C9 1192/4885CYP1A2 720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.