Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Triethylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137364 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP1A2SMN1; SMN2LMNA | |
| SCHEMBL29249377 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP1A2SMN1; SMN2LMNA | |
| SCHEMBL28704841 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP1A2SMN1; SMN2LMNA | |
| SCHEMBL28618062 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP1A2SMN1; SMN2LMNA | |
| Pentaethylene Glycol SCHEMBL3466434 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP1A2SMN1; SMN2LMNA | |
| Hexaethylene Glycol SCHEMBL11280667 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP1A2SMN1; SMN2LMNA | |
| Tetraethylene Glycol SCHEMBL1145155 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP1A2SMN1; SMN2LMNA | |
| Hexaethylene Glycol SCHEMBL4379136 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP1A2SMN1; SMN2LMNA | |
| Tetraethylene Glycol SCHEMBL3062384 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP1A2SMN1; SMN2LMNA | |
| SCHEMBL27633211 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP1A2SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119931671-A | Silicon-calcium-potassium-magnesium type soil conditioner and preparation method thereof | 鄂尔多斯市蒙泰铝业有限责任公司 | 2025-05-06 | — | — | CN | claimed |
| CN-117717506-B | Modified cellulose-based arborescent aloe freeze-dried powder and preparation method thereof | 山东爱维德生物科技有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-117659319-B | Phenolic resin for high-wettability abrasive grinding tool and preparation method thereof | 山东宇世巨化工有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-117717506-A | Modified cellulose-based arborescent aloe freeze-dried powder and preparation method thereof | 山东爱维德生物科技有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-117659319-A | Phenolic resin for high-wettability abrasive grinding tool and preparation method thereof | 山东宇世巨化工有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-117070138-A | Quick-drying alkyd resin paint and preparation method thereof | 山东齐鲁漆业有限公司 | 2023-11-17 | — | — | CN | claimed |
| CN-115991858-B | Preparation method of high-temperature-resistant phenolic resin gel material | 山东宇世巨化工有限公司 | 2023-06-02 | — | — | CN | claimed |
| CN-115991858-A | Preparation method of high-temperature-resistant phenolic resin gel material | 山东宇世巨化工有限公司 | 2023-04-21 | — | — | CN | claimed |
| CN-119931671-A | Silicon-calcium-potassium-magnesium type soil conditioner and preparation method thereof | 鄂尔多斯市蒙泰铝业有限责任公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-116768752-B | Temperature-sensitive organic luminescent molecule, organic luminescent molecule doped film, and preparation method and application thereof | 北京化工大学 | 2025-04-25 | — | — | CN | disclosed |
| CN-119431385-A | IRAK4 degradation agent, pharmaceutical composition and pharmaceutical application thereof | 中国科学院上海药物研究所 | 2025-02-14 | — | — | CN | disclosed |
| WO-2025031294-A1 | IRAK4 DEGRADER AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL USE THEREOF | 中国科学院上海药物研究所 | 2025-02-13 | — | — | WO | disclosed |
| CN-113711121-B | Low dimerization viologen electrochromic compounds and devices | 金泰克斯公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-117717506-B | Modified cellulose-based arborescent aloe freeze-dried powder and preparation method thereof | 山东爱维德生物科技有限公司 | 2024-06-04 | — | — | CN | disclosed |
| US-20050064468-A1 | concentration, removing or separation of nucleotide bases or nucleotide sequences containing bases from solid supports | IBC ADVANCED TECHNOLOGIES, INC. | 2005-03-24 | — | — | US | disclosed |
| EP-1453602-A4 | COMPOSITIONS AND METHODS FOR SEPARATING HETEROCYCLIC AROMATIC AMINE BASES, NUCLEOSIDES, NUCLEOTIDES, AND NUCLEOTIDE SEQUENCES | IBC ADVANCED TECH INC (US) | 2005-01-12 | — | — | EP | disclosed |
| EP-1453602-A2 | COMPOSITIONS AND METHODS FOR SEPARATING HETEROCYCLIC AROMATIC AMINE BASES, NUCLEOSIDES, NUCLEOTIDES, AND NUCLEOTIDE SEQUENCES | IBC ADVANCED TECHNOLOGIES, INC. (US) | 2004-09-08 | — | — | EP | disclosed |
| US-6774082-B2 | COMPOSITION FOR USE IN THE SEPARATION OF PREFERENTIAL BIOPOLYMERS FROM SAMPLE | IBC ADVANCED TECHNOLOGIES, INC. | 2004-08-10 | — | — | US | disclosed |
| US-20030050458-A1 | Compositions and methods for separating heterocyclic aromatic amine bases, nucleosides, nucleotides, and nucleotide sequences | IBC ADVANCED TECHNOLOGIES, INC. | 2003-03-13 | — | — | US | disclosed |
| WO-2002092766-A2 | COMPOSITIONS AND METHODS FOR SEPARATING HETEROCYCLIC AROMATIC AMINE BASES, NUCLEOSIDES, NUCLEOTIDES, AND NUCLEOTIDE SEQUENCES | IBC ADVANCED TECHNOLOGIES, INC. (US) | 2002-11-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030050458-A1 | Compositions and methods for separating heterocyclic aromatic amine bases, nucleosides, nucleotides, and nucleotide sequences | NUDT1, ATIC, PNP | ALDH1A1 2347/4885CYP2C9 3214/4885CYP1A2 3998/4885 |
| US-20050064468-A1 | concentration, removing or separation of nucleotide bases or nucleotide sequences containing bases from solid supports | NUDT1, PCNA, NSUN2 | ALDH1A1 2730/4885CYP2C9 3680/4885CYP1A2 4409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.