SCHEMBL3229364

SCHEMBL3229364

Cc1ccc(CS(N)(=O)=O)cc1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA1 P00915 10/20 0.60
CA2 P00918 10/20 0.60
CA9 Q16790 9/20 0.60
CA5A P35218 3/20 0.60
CA12 O43570 4/20 0.50
CA7 P43166 2/20 0.50
KIF11 P52732 1/20 0.50
CA3 P07451 1/20 0.50
CA6 P23280 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
KMT2A Q03164 1/20 0.48
CA4 P22748 1/20 0.46
CYP1A2 P05177 1/20 0.44
CYP2A6 P11509 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
ALDH1A1 P00352 1/20 0.43
AGXT P21549 1/20 0.43
IDO1 P14902 1/20 0.42
GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4057569 0.98 CA1 (0.58) CA1CA2CA9CA5ACA12
Phenylmethanesulfonamide SCHEMBL27949309 0.89 CA2 (0.79) CA1CA2CA9CA5ACA12
Triethylene Glycol SCHEMBL10695052 0.82 CA1 (0.45) CA1CA2CA9CA5ACA12
SCHEMBL4868635 0.81 CA2 (0.61) CA1CA2CA9CA5AKIF11
SCHEMBL4400952 0.80 KMT2A (0.62) CA1CA2CA9KMT2ACYP1A2
SCHEMBL515055 0.78 KMT2A (0.50) CA1CA2CA9CA5ACA12
SCHEMBL2984207 0.78 CA1 (0.62) CA1CA2CA9CA5ACA12
SCHEMBL4573294 0.78 CA2 (0.62) CA1CA2CA9CA5ACA12
SCHEMBL788780 0.78 KMT2A (0.50) CA1CA2CA9CA5ACA12
SCHEMBL1044703 0.77 RECQL (0.64) CA1CA2CA9CA5ACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219809-A Fluorine-containing polymer, preparation method thereof and ion exchange membrane 佛山绿动氢能科技有限公司 2024-12-31 CN disclosed
US-20230159469-A1 NOVEL PHTHALAZINE DERIVATIVE HAVING ECTONUCLOEOTIDE PYROPHOSPHATASE/PHOSPHODIESTE RASE INHIBITORY ACTIVITY, AND USE THEREOF TXINNO BIOSCIENCE INC. (KR) 2023-05-25 US disclosed
US-11518739-B2 Sulfonamide carboxamide compounds INFLAZOME LIMITED (IE) 2022-12-06 US disclosed
EP-3849664-A1 PHENOXY-PYRIDYL-PYRIMIDINE COMPOUNDS AND METHODS OF USE Genentech, Inc. (US) 2021-07-21 EP disclosed
US-10851098-B2 Azole amides and amines as alpha v integrin inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2020-12-01 US disclosed
US-20200216389-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS INFLAZOME LIMITED (IE) 2020-07-09 US disclosed
CN-111303146-A 3-cyanopyridine compound, pharmaceutical composition containing same, preparation method and application thereof 中国科学院上海药物研究所 2020-06-19 CN disclosed
WO-2020119590-A1 3-CYANOPYRIDINE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR, AND USES THEREOF. 中国科学院上海药物研究所 2020-06-18 WO disclosed
WO-2020119590-A1 3-CYANOPYRIDINE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR, AND USES THEREOF. 中国科学院上海药物研究所 2020-06-18 WO disclosed
WO-2020056089-A1 PHENOXY-PYRIDYL-PYRIMIDINE COMPOUNDS AND METHODS OF USE GENENTECH, INC. (US) 2020-03-19 WO disclosed
US-4891427-A BACTERICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-01-02 US disclosed
US-4876251-A ANTIBIOTICS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-10-24 US disclosed
US-4851422-A Antibiotic 2-(3-oxo-2-isoxazolidinyl)-5-oxo-2-tetrahydrofuran-carboxylates TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-07-25 US disclosed
EP-0271829-A2 Delta-hydroxy-beta-lysine derivatives and their production Takeda Chemical Industries, Ltd. (JP) 1988-06-22 EP disclosed
EP-0250096-A1 Isoxazolone derivatives and production thereof Takeda Chemical Industries, Ltd. (JP) 1987-12-23 EP disclosed
EP-0249909-A1 Tricyclic penam compounds, their production and their use Takeda Chemical Industries, Ltd. (JP) 1987-12-23 EP disclosed
EP-0219923-A1 Antibiotic derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1987-04-29 EP disclosed
CN-86102923-A The method for preparing antibiotic derivatives 1986-11-12 CN disclosed
EP-0191989-A1 Antibiotic isoxazole derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1986-08-27 EP disclosed
US-4428956-A GLYCOLATE OXIDASE INHIBITORS MERCK & CO., INC. (US) 1984-01-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200216389-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS NLRP3, NOD1, PYCARD CA1 2274/4885CA2 1407/4885CA9 2516/4885
US-10851098-B2 Azole amides and amines as alpha v integrin inhibitors ITGAV, ITGB1, ITGA1 CA1 1863/4885CA2 1889/4885CA9 695/4885
US-20230159469-A1 NOVEL PHTHALAZINE DERIVATIVE HAVING ECTONUCLOEOTIDE PYROPHOSPHATASE/PHOSPHODIESTE RASE INHIBITORY ACTIVITY, AND USE THEREOF ENPP1, ENPP3, PPA1 CA1 2081/4885CA2 1041/4885CA9 2693/4885
US-11518739-B2 Sulfonamide carboxamide compounds NLRP3, PYCARD, NOD1 CA1 2278/4885CA2 1228/4885CA9 2142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.