Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693464 | 0.85 | PDE4A (0.63) | TSHRMAPK1SMN1; SMN2USP2 | |
| SCHEMBL10694058 | 0.85 | PDE4A (0.63) | TSHRMAPK1SMN1; SMN2USP2 | |
| SCHEMBL10693479 | 0.84 | PDE4A (0.61) | KMT2AMEN1ALDH1A1HPGDTSHR | |
| SCHEMBL9350641 | 0.78 | CNOT7 (0.53) | KMT2AMEN1ALDH1A1HPGDTSHR | |
| SCHEMBL10695298 | 0.77 | BRD4 (0.67) | KMT2AMEN1ALDH1A1MAPK1KDM4E | |
| SCHEMBL11058131 | 0.77 | PDE4A (0.62) | — | |
| SCHEMBL11057370 | 0.75 | PDE4A (0.48) | KMT2ACNOT7 | |
| SCHEMBL7567218 | 0.75 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1HPGDTSHR | |
| SCHEMBL10697104 | 0.75 | PDE4A (0.79) | KMT2AMEN1ALDH1A1HPGDTSHR | |
| SCHEMBL7558690 | 0.74 | POLB (0.66) | KMT2AMEN1ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269451-A2 | A new labelling design for a binding assay reagent | SCLAVO, INC. (US) | 1988-06-01 | — | — | EP | disclosed |
| EP-0260127-A2 | Xanthine derivatives, their preparation and pharmaceutical compositions containing them | BEECHAM - WUELFING GmbH & Co. KG (DE) | 1988-03-16 | — | — | EP | disclosed |