Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | EBP | Q15125 | 2/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 3/20 | 0.45 |
| ▸ | HTR2B | P41595 | 3/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10034619 | 0.90 | ATM (0.54) | ATMKDM4EPOLBCYP19A1CYP1A2 | |
| SCHEMBL1261811 | 0.80 | CA2 (0.55) | ATMKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10343404 | 0.79 | ATM (0.70) | ATMKDM4EPOLBCYP19A1CYP1A2 | |
| SCHEMBL30869991 | 0.79 | ATM (0.70) | ATMKDM4EPOLBCYP19A1CYP1A2 | |
| SCHEMBL8803380 | 0.79 | CALM1 (0.51) | SIGMAR1DRD2DRD4DRD3 | |
| SCHEMBL13271127 | 0.79 | PPARG (0.42) | HTR2ADRD4 | |
| SCHEMBL678094 | 0.79 | CALM1 (0.45) | ATMKDM4EPOLBDRD4 | |
| SCHEMBL10975422 | 0.78 | POLB (0.56) | ATMKDM4EPOLBCA2 | |
| SCHEMBL1455517 | 0.78 | MAPT (0.47) | — | |
| SCHEMBL20327297 | 0.78 | ABCB1 (0.48) | ATMKDM4EPOLBCYP19A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267439-A2 | Alpha-(phenylalkyl) pyridinealkanol derivatives | G.D. Searle & Co. (US) | 1988-05-18 | — | — | EP | disclosed |