Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890855 | 0.84 | ALDH1A1 (0.67) | POLBSMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL9700597 | 0.83 | HTR1A (0.49) | POLBATMSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1965700 | 0.82 | POLB (0.59) | POLBATMSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7435099 | 0.81 | ATM (0.76) | POLBATMSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL10034619 | 0.80 | ATM (0.54) | POLBATMKDM4EMAPTCA12 | |
| Hydrochloric Acid SCHEMBL11808765 | 0.80 | ATM (0.73) | POLBATMSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL10695511 | 0.78 | ATM (0.51) | POLBATMKDM4ECA2 | |
| SCHEMBL11934839 | 0.77 | KMT2A (0.53) | POLBATMSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL13438704 | 0.77 | KMT2A (0.53) | POLBATMSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1966411 | 0.77 | ATM (0.69) | POLBATMSMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0086256-B1 | 1-(2,4-DICHLOROPHENOXY)-3-(3,4-DIMETHOXY-BETA-PHENETHYLAMINO)-PROPAN-2-0L, PROCESSES FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | VEB Arzneimittelwerk Dresden (DD) | 1985-08-21 | — | — | EP | claimed |
| EP-0086256-B1 | 1-(2,4-DICHLOROPHENOXY)-3-(3,4-DIMETHOXY-BETA-PHENETHYLAMINO)-PROPAN-2-0L, PROCESSES FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | VEB Arzneimittelwerk Dresden (DD) | 1985-08-21 | — | — | EP | disclosed |