Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.47 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.47 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695511 | 0.90 | ATM (0.51) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL1261811 | 0.83 | CA2 (0.55) | ATMKDM4ECA2CYP1A2CYP3A4 | |
| SCHEMBL7360040 | 0.83 | ADRA1A (0.49) | ATMKDM4EPOLBSIGMAR1 | |
| SCHEMBL10975422 | 0.80 | POLB (0.56) | ATMKDM4ECA2POLBMAPT | |
| SCHEMBL2689229 | 0.79 | SLC6A4 (0.64) | ATMKDM4ECYP19A1 | |
| SCHEMBL2689969 | 0.79 | SLC6A4 (0.64) | ATMKDM4E | |
| SCHEMBL13271127 | 0.78 | PPARG (0.42) | LYPLA1LYPLA2ABHD16A | |
| SCHEMBL31157848 | 0.78 | CYP19A1 (0.77) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL16641094 | 0.78 | CYP19A1 (0.77) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL6631330 | 0.78 | CA2 (0.49) | ATMKDM4ECA2POLBCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120041019-A1 | PROTEASE INHIBITORS | AMPLYX PHARMACEUTICALS, INC. | 2012-02-16 | — | — | US | disclosed |
| US-20120041019-A1 | PROTEASE INHIBITORS | AMPLYX PHARMACEUTICALS, INC. | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041019-A1 | PROTEASE INHIBITORS | SERPINB1, PREP, DNPEP | ATM 4362/4885KDM4E 858/4885CA2 2215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.