Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 9/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695581 | 0.85 | TBXAS1 (0.60) | KMT2ATBXAS1NAPRTCYP1A2CYP3A4 | |
| SCHEMBL10695456 | 0.82 | KMT2A (0.53) | MEN1KMT2ATBXAS1 | |
| SCHEMBL1538161 | 0.78 | NAPRT (0.57) | TBXAS1NAPRTTRPV1CYP1A2CYP3A4 | |
| SCHEMBL9520246 | 0.75 | TBXAS1 (0.62) | TBXAS1NAPRTTRPV1TDP1L3MBTL1 | |
| SCHEMBL10695814 | 0.74 | MEN1 (0.44) | MEN1KMT2ATBXAS1TRPV1TDP1 | |
| SCHEMBL7280697 | 0.74 | NAPRT (0.61) | KMT2ATBXAS1NAPRTCYP1A2CYP3A4 | |
| SCHEMBL3373232 | 0.74 | TBXAS1 (0.55) | MEN1KMT2ATBXAS1NAPRTTRPV1 | |
| SCHEMBL3253168 | 0.73 | NAPRT (0.74) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9732407 | 0.73 | TBXAS1 (0.52) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL19578340 | 0.73 | NAPRT (0.62) | MEN1KMT2ATBXAS1NAPRTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267439-A2 | Alpha-(phenylalkyl) pyridinealkanol derivatives | G.D. Searle & Co. (US) | 1988-05-18 | — | — | EP | disclosed |