SCHEMBL10695578

SCHEMBL10695578

Cc1ccccc1Oc1ccc[nH]1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
TSHR P16473 2/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 2/20 0.36
SLC6A3 Q01959 1/20 0.36
AR P10275 4/20 0.36
ALDH1A1 P00352 3/20 0.36
CYP1A2 P05177 2/20 0.36
HPGD P15428 2/20 0.36
CYP2C19 P33261 2/20 0.36
LMNA P02545 1/20 0.36
CYP2C9 P11712 1/20 0.36
TP53 P04637 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
MRGPRX1 Q96LB2 2/20 0.35
HTR1A P08908 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10696727 0.79 HTR1A (0.42) SMN1; SMN2KMT2ATSHRNPC1RAB9A
SCHEMBL10711010 0.76 RHEB (0.46) SMN1; SMN2KMT2ATSHRRAB9ASLC6A2
SCHEMBL9709071 0.76
SCHEMBL29637724 0.75 TSHR (0.65) SMN1; SMN2MEN1KMT2ATSHRNPC1
SCHEMBL9651942 0.75 DAO (0.35)
SCHEMBL127000 0.75 TSHR (0.65) SMN1; SMN2MEN1KMT2ATSHRNPC1
Methyl Alcohol SCHEMBL10895232 0.73 DAO (0.36) MEN1KMT2A
Fluoride SCHEMBL27757467 0.73 TSHR (0.62) SMN1; SMN2MEN1KMT2ATSHRNPC1
Phosphine SCHEMBL22634020 0.73 TSHR (0.62) SMN1; SMN2MEN1KMT2ATSHRNPC1
Nitrogen SCHEMBL28056541 0.71 TSHR (0.60) SMN1; SMN2MEN1KMT2ATSHRNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0271260-A2 Supersensitization of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-15 EP claimed
EP-0271260-A2 Supersensitization of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-15 EP disclosed