SCHEMBL10696727

SCHEMBL10696727

Cc1ccc(Oc2ccc[nH]2)c(C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 2/20 0.42
HTR3A P46098 2/20 0.42
GAA P10253 2/20 0.36
L3MBTL1 Q9Y468 4/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 1/20 0.36
NFKB1 P19838 1/20 0.36
RAB9A P51151 1/20 0.36
NFKB2 Q00653 1/20 0.36
KMT2A Q03164 1/20 0.36
RELA Q04206 1/20 0.36
ACHE P22303 1/20 0.35
MAPT P10636 1/20 0.35
SCN10A Q9Y5Y9 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
PDPK1 O15530 1/20 0.33
RET P07949 1/20 0.33
MRGPRX4 Q96LA9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10695578 0.79 SMN1; SMN2 (0.47) HTR1ASMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL9565223 0.77 PTGDR2 (0.39) L3MBTL1NPC1RAB9AKMT2AMAPT
SCHEMBL4950654 0.76 HTR1A (0.50) HTR1AHTR3AGAAL3MBTL1SMN1; SMN2
SCHEMBL31666386 0.76 HTR1A (0.50) HTR1AHTR3AGAAL3MBTL1SMN1; SMN2
SCHEMBL7867531 0.73 ALDH1A1 (0.49) GAAL3MBTL1KMT2AACHEMAPT
SCHEMBL8737305 0.71 HTR1A (0.55) HTR1AHTR3AGAAL3MBTL1SMN1; SMN2
SCHEMBL9651942 0.71 DAO (0.35) GAAMAPT
SCHEMBL28452075 0.70 SLC6A4 (0.45) HTR1AHTR3AGAAL3MBTL1KMT2A
SCHEMBL8484975 0.69 NTRK1 (0.48) HTR1AHTR3AGAASMN1; SMN2HPGD
SCHEMBL446449 0.69 AR (0.47) HTR1AHTR3AGAAL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0271260-A2 Supersensitization of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-15 EP claimed
EP-0271260-A2 Supersensitization of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-15 EP disclosed