Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 6/20 | 0.49 |
| ▸ | CDK1 | P06493 | 5/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.49 |
| ▸ | CCNA1 | P78396 | 5/20 | 0.49 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696476 | 0.81 | BRD4 (0.47) | CDK2CCNA2CCNA1BRD4PDPK1 | |
| SCHEMBL10695889 | 0.79 | CDK2 (0.48) | CDK2CDK1CCNB1CCNA2CCNA1 | |
| SCHEMBL10697819 | 0.74 | BRAF (0.41) | BRD4PDPK1ALDH1A1GAALMNA | |
| SCHEMBL3969724 | 0.74 | BRD4 (0.45) | BRD4PDPK1ALDH1A1LMNACYP3A4 | |
| SCHEMBL10441257 | 0.70 | BRD4 (0.42) | CDK2CDK1CCNB1CCNA2CCNA1 | |
| SCHEMBL8691506 | 0.69 | BRD4 (0.38) | CDK2CDK1CCNB1CCNA2CCNA1 | |
| SCHEMBL22966379 | 0.67 | ALDH1A1 (0.47) | CDK2BRD4PDPK1ALDH1A1LMNA | |
| SCHEMBL3960229 | 0.65 | HTT (0.41) | CDK2CDK1CCNB1CCNA2CCNA1 | |
| SCHEMBL4069873 | 0.65 | ALDH1A1 (0.39) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7108989 | 0.64 | PI4KA (0.50) | CDK2BRD4PDPK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254588-A1 | Imidazo[4,5-b] pyridine compounds, process for preparing same and pharmaceutical compositions containing same | TOKYO TANABE COMPANY LIMITED (JP) | 1988-01-27 | — | — | EP | claimed |