Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | CDC7 | O00311 | 4/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696476 | 0.78 | BRD4 (0.47) | BRD4ALDH1A1HSD17B10KDM4EKMT2A | |
| SCHEMBL10695889 | 0.75 | CDK2 (0.48) | BRD4ALDH1A1HTTSMN1; SMN2LMNA | |
| SCHEMBL10695854 | 0.74 | CDK2 (0.49) | BRD4ALDH1A1HSD17B10KDM4ECYP3A4 | |
| SCHEMBL18188313 | 0.74 | MAPT (0.46) | BRD4CDC7DBF4ALDH1A1MAPT | |
| SCHEMBL3969724 | 0.74 | BRD4 (0.45) | BRAFBRD4CDC7DBF4ALDH1A1 | |
| SCHEMBL30788403 | 0.67 | ALDH1A1 (0.46) | BRD4ALDH1A1HSD17B10HSP90AA1HSP90AB1 | |
| SCHEMBL22830483 | 0.67 | ALDH1A1 (0.46) | BRD4ALDH1A1HSD17B10HSP90AA1HSP90AB1 | |
| SCHEMBL5036347 | 0.66 | MAPT (0.48) | ALDH1A1MAPTHSD17B10KDM4EKMT2A | |
| SCHEMBL5218807 | 0.66 | NPC1 (0.45) | ALDH1A1MAPTHSD17B10KDM4EKMT2A | |
| SCHEMBL1165562 | 0.64 | ALDH1A1 (0.46) | BRD4CDC7DBF4ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254588-A1 | Imidazo[4,5-b] pyridine compounds, process for preparing same and pharmaceutical compositions containing same | TOKYO TANABE COMPANY LIMITED (JP) | 1988-01-27 | — | — | EP | claimed |