Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695889 | 0.86 | CDK2 (0.48) | BRD4SMN1; SMN2LMNAHTTPDPK1 | |
| SCHEMBL10695854 | 0.81 | CDK2 (0.49) | BRD4SMN1; SMN2LMNAPDPK1ALDH1A1 | |
| SCHEMBL10697819 | 0.78 | BRAF (0.41) | BRD4SMN1; SMN2HPGDTSHRLMNA | |
| SCHEMBL3969724 | 0.78 | BRD4 (0.45) | BRD4LMNAPDPK1ALDH1A1CYP3A4 | |
| SCHEMBL22966379 | 0.74 | ALDH1A1 (0.47) | BRD4SMN1; SMN2LMNAHTTPDPK1 | |
| SCHEMBL6407612 | 0.74 | KDM4E (0.42) | SMN1; SMN2HPGDTSHRLMNAALDH1A1 | |
| SCHEMBL8691506 | 0.72 | BRD4 (0.38) | BRD4SMN1; SMN2TSHRLMNAHTT | |
| SCHEMBL3960229 | 0.71 | HTT (0.41) | BRD4SMN1; SMN2HPGDHTTPDPK1 | |
| SCHEMBL2493987 | 0.71 | BRD4 (0.51) | BRD4LMNAPDPK1ALDH1A1TP53 | |
| SCHEMBL10441257 | 0.70 | BRD4 (0.42) | BRD4SMN1; SMN2LMNAPDPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254588-A1 | Imidazo[4,5-b] pyridine compounds, process for preparing same and pharmaceutical compositions containing same | TOKYO TANABE COMPANY LIMITED (JP) | 1988-01-27 | — | — | EP | claimed |