Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 4/20 | 0.35 |
| ▸ | PDE4A | P27815 | 4/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696473 | 0.87 | LTA4H (0.39) | LTA4HNPC1L3MBTL1PDE5ABACE1 | |
| SCHEMBL10695851 | 0.79 | PDE5A (0.36) | LTA4HNPC1KDM4EL3MBTL1PDE5A | |
| SCHEMBL3969727 | 0.78 | BACE1 (0.45) | LTA4HNPC1L3MBTL1SMN1; SMN2BACE1 | |
| SCHEMBL10697815 | 0.76 | LTA4H (0.36) | LTA4HSMN1; SMN2BACE1MKNK1MKNK2 | |
| SCHEMBL3960228 | 0.71 | LTA4H (0.52) | LTA4HNPC1KDM4EPDE4APDE4B | |
| SCHEMBL231309 | 0.70 | LTA4H (0.48) | LTA4HNPC1KDM4EPDE4APDE4B | |
| SCHEMBL10163442 | 0.69 | LTA4H (0.50) | LTA4HNPC1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL7149525 | 0.68 | LTA4H (0.35) | LTA4HBACE1ASAH1KMT2AMKNK1 | |
| SCHEMBL13749801 | 0.68 | LTA4H (0.49) | LTA4HSMN1; SMN2LMNATSHRHTT | |
| SCHEMBL30178291 | 0.67 | LTA4H (0.41) | LTA4HNPC1KDM4EBRD4BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254588-A1 | Imidazo[4,5-b] pyridine compounds, process for preparing same and pharmaceutical compositions containing same | TOKYO TANABE COMPANY LIMITED (JP) | 1988-01-27 | — | — | EP | claimed |