Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696473 | 0.79 | LTA4H (0.39) | LTA4HMKNK1MKNK2BACE1 | |
| SCHEMBL10695888 | 0.76 | LTA4H (0.40) | LTA4HSMN1; SMN2MKNK1MKNK2BACE1 | |
| SCHEMBL10695851 | 0.75 | PDE5A (0.36) | LTA4HMKNK1MKNK2BACE1 | |
| SCHEMBL3969727 | 0.73 | BACE1 (0.45) | LTA4HSMN1; SMN2MKNK1MKNK2BACE1 | |
| SCHEMBL18188312 | 0.69 | LTA4H (0.35) | LTA4HHCAR2MKNK1MKNK2BACE1 | |
| SCHEMBL231309 | 0.66 | LTA4H (0.48) | LTA4HSMN1; SMN2GRM2MKNK1MKNK2 | |
| SCHEMBL31229913 | 0.64 | LTA4H (0.39) | LTA4HSMN1; SMN2MKNK1MKNK2BACE1 | |
| SCHEMBL9598840 | 0.64 | LTA4H (0.52) | LTA4HSMN1; SMN2GRM2MAPK14 | |
| SCHEMBL31608474 | 0.63 | HTT (0.49) | — | |
| SCHEMBL13296647 | 0.63 | LTA4H (0.38) | LTA4HMKNK1MKNK2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254588-A1 | Imidazo[4,5-b] pyridine compounds, process for preparing same and pharmaceutical compositions containing same | TOKYO TANABE COMPANY LIMITED (JP) | 1988-01-27 | — | — | EP | claimed |