Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695888 | 0.87 | LTA4H (0.40) | LTA4HBACE1KMT2ANPC1RAB9A | |
| SCHEMBL10695851 | 0.82 | PDE5A (0.36) | LTA4HBACE1KMT2ANPC1RAB9A | |
| SCHEMBL3969727 | 0.80 | BACE1 (0.45) | LTA4HBACE1KMT2ANPC1RAB9A | |
| SCHEMBL10697815 | 0.79 | LTA4H (0.36) | LTA4HBACE1MKNK1MKNK2 | |
| SCHEMBL28860663 | 0.75 | TDP1 (0.48) | KMT2ANPC1LMNAPKMTSHR | |
| SCHEMBL231309 | 0.73 | LTA4H (0.48) | LTA4HBACE1KMT2ANPC1RAB9A | |
| SCHEMBL16302882 | 0.71 | HRH4 (0.32) | — | |
| SCHEMBL3960228 | 0.70 | LTA4H (0.52) | LTA4HNPC1RAB9AASAH1LMNA | |
| SCHEMBL16302883 | 0.70 | HPGD (0.36) | ALDH1A1TSHRNPSR1L3MBTL1 | |
| SCHEMBL30178291 | 0.70 | LTA4H (0.41) | LTA4HBACE1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254588-A1 | Imidazo[4,5-b] pyridine compounds, process for preparing same and pharmaceutical compositions containing same | TOKYO TANABE COMPANY LIMITED (JP) | 1988-01-27 | — | — | EP | claimed |