Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29126607 | 0.80 | LMNA (0.47) | LMNASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL7270618 | 0.78 | SMN1; SMN2 (0.60) | LMNASMN1; SMN2TLR9TP53NPC1 | |
| SCHEMBL9565278 | 0.75 | PLAAT3 (0.34) | LMNASMN1; SMN2MAPTALDH1A1HTT | |
| SCHEMBL11344361 | 0.75 | LMNA (0.49) | LMNASMN1; SMN2TLR9TP53NPC1 | |
| SCHEMBL4852552 | 0.75 | IRAK4 (0.38) | LMNASMN1; SMN2TLR9TP53NPC1 | |
| SCHEMBL2411422 | 0.75 | SMN1; SMN2 (0.43) | LMNASMN1; SMN2TLR9TP53NPC1 | |
| SCHEMBL9626161 | 0.74 | LMNA (0.47) | LMNASMN1; SMN2TLR9TP53NPC1 | |
| SCHEMBL7696606 | 0.73 | ALDH1A1 (0.43) | LMNASMN1; SMN2TLR9TP53NPC1 | |
| SCHEMBL32665306 | 0.73 | LMNA (0.42) | LMNASMN1; SMN2TLR9TP53NPC1 | |
| SCHEMBL28858783 | 0.73 | LMNA (0.42) | LMNASMN1; SMN2TLR9TP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255890-A1 | Process for the reaction of amines with heterocyclic reactive compounds | BAYER AG (DE) | 1988-02-17 | — | — | EP | disclosed |