SCHEMBL544657

SCHEMBL544657

C=C(C(=O)OC)C(C=CC#N)C=Cc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.38
LMNA P02545 1/20 0.37
CYP3A4 P08684 2/20 0.37
CYP1A2 P05177 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CMA1 P23946 2/20 0.35
CNR2 P34972 1/20 0.35
APP P05067 1/20 0.34
ABCG2 Q9UNQ0 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 1/20 0.33
GLA P06280 1/20 0.33
CTSC P53634 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butadiene SCHEMBL11122770 0.96 TDP1 (0.36) TDP1LMNACYP3A4CYP1A2ALDH1A1
SCHEMBL10932584 0.93 LMNA (0.38) TDP1LMNACYP3A4CYP1A2ALDH1A1
SCHEMBL437822 0.86 AKR1B10 (0.36) LMNACYP3A4ALDH1A1APPTSHR
Styrene SCHEMBL7727957 0.85 ALDH1A1 (0.33) LMNACYP3A4ALDH1A1APPTSHR
Acrylonitrile SCHEMBL9249811 0.85 LMNA (0.37) TDP1LMNACYP3A4CYP1A2ALDH1A1
SCHEMBL1425048 0.85 CYP1A2 (0.41) TDP1LMNACYP3A4CYP1A2ALDH1A1
Methoxymethane SCHEMBL17812950 0.85 ALDH1A1 (0.34) TDP1LMNACYP3A4CYP1A2ALDH1A1
Butadiene SCHEMBL5050055 0.84 TSHR (0.40) TDP1LMNACYP3A4ALDH1A1APP
SCHEMBL533420 0.83 AKR1B10 (0.35) TDP1LMNACYP3A4CYP1A2ALDH1A1
SCHEMBL5418266 0.83 HDAC3 (0.45) TDP1LMNACYP3A4CYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 604 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119409896-B Preparation method and application of ABS grafted latex 万华化学集团股份有限公司 2026-05-19 CN claimed
CN-122060274-A ASA-PMA blending modified composite particle and preparation method thereof 安徽省仕隆新材料科技有限公司 2026-05-19 CN claimed
US-12344735-B2 Thermoplastic resin composition, method of preparing the same, and molded article manufactured using the same LG CHEM, LTD. (KR) 2025-07-01 US claimed
CN-118978618-B Agglomerated particles and preparation method and application thereof 辽宁金发科技有限公司 2025-04-22 CN claimed
CN-119798552-A MABS graft copolymer resin, preparation method and transparent MABS resin composition 万华化学集团股份有限公司 2025-04-11 CN claimed
CN-118978619-B Agglomerated particles, preparation method thereof and resin composition containing agglomerated particles 辽宁金发科技有限公司 2025-03-25 CN claimed
CN-119409896-A Preparation method and application of ABS grafted latex 万华化学集团股份有限公司 2025-02-11 CN claimed
CN-119286176-A Semi-transparent electroplated ABS material with high light transmittance and preparation method and application thereof 上海锦湖日丽塑料有限公司 2025-01-10 CN claimed
CN-118978618-A Agglomerated particles and preparation method and application thereof 辽宁金发科技有限公司 2024-11-19 CN claimed
CN-118978619-A Agglomerated particles, preparation method thereof and resin composition containing agglomerated particles 辽宁金发科技有限公司 2024-11-19 CN claimed
WO-2005080503-A1 IMPACT-MODIFIED COMPOSITIONS AND METHOD GENERAL ELECTRIC COMPANY (US) 2005-09-01 WO claimed
US-20050171297-A1 Impact-modified compositions and method GENERAL ELECTRIC COMPANY 2005-08-04 US claimed
WO-2005027111-A1 LIMITED PLAY DATA STORAGE MEDIA AND METHOD FOR LIMITING ACCESS TO DATA THEREON GENERAL ELECTRIC COMPANY (US) 2005-03-24 WO claimed
US-20050053865-A1 Limited play data storage media and method for limiting access to data thereon SABIC INNOVATIVE PLASTICS IP B.V. 2005-03-10 US claimed
EP-1000966-B1 Chlorinated vinyl chloride resin composition KANEKA CORP (JP) 2005-02-02 EP claimed
CN-1177876-C Process for preparing thermoplastic transparent resin LG��ѧ��ʽ���� 2004-12-01 CN claimed
CN-1372579-A Method for preparing thermoplastic transparent resin LG CHEMICAL LTD (KR) 2002-10-02 CN claimed
US-4701495-A HEAT RESISTANT, IMPACT STRENGTH MOLDING MATERIAL BLEND OF ACRYLONITRILE, 2-ISOPROPENYLNAPHTHALENE, AND METHYLSTYRENE WITH A GRAFT RUBBER POLYMER KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-10-20 US claimed
US-4692295-A USING A LOWER STRETCHING FORCE BY INCLUDING A HIGH MOLECULAR WEIGHT ADDITIVE ADDITION POLYMER PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1987-09-08 US claimed
US-4117034-A SYNERGISTIC ENHANCEMENT OF IMPACT PROPERTIES BORG-WARNER CORPORATION (US) 1978-09-26 US claimed