SCHEMBL10695943

SCHEMBL10695943

COc1cc(C=O)ccc1OC/C=C/COc1ccc(C=O)cc1OC

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.75
ALDH1A1 P00352 12/20 0.70
TSHR P16473 1/20 0.70
MAPT P10636 6/20 0.60
SMN1; SMN2 Q16637 4/20 0.60
HTT P42858 2/20 0.60
LMNA P02545 1/20 0.60
NPSR1 Q6W5P4 1/20 0.60
HPGD P15428 4/20 0.59
TRIM24 O15164 1/20 0.59
ALDH5A1 P51649 1/20 0.59
ABAT P80404 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
TRIM33 Q9UPN9 1/20 0.59
NPC1 O15118 1/20 0.57
RAB9A P51151 1/20 0.57
POLB P06746 1/20 0.56
TTR P02766 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
CYP1A2 P05177 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10695955 1.00 FDPS (0.75) FDPSALDH1A1TSHRMAPTSMN1; SMN2
SCHEMBL17941258 0.90 FDPS (0.75) FDPSALDH1A1TSHRMAPTSMN1; SMN2
SCHEMBL29652045 0.87 FDPS (0.71) FDPSALDH1A1TSHRMAPTSMN1; SMN2
SCHEMBL1396839 0.87 FDPS (0.71) FDPSALDH1A1TSHRMAPTSMN1; SMN2
SCHEMBL5973815 0.86 FDPS (1.00) FDPSALDH1A1TSHRMAPTSMN1; SMN2
SCHEMBL25273898 0.84 FDPS (0.77) FDPSALDH1A1TSHRMAPTSMN1; SMN2
SCHEMBL9442186 0.84 FDPS (0.90) FDPSALDH1A1TSHRMAPTSMN1; SMN2
SCHEMBL356800 0.84 FDPS (0.77) FDPSALDH1A1TSHRMAPTSMN1; SMN2
SCHEMBL5599547 0.84 MTNR1A (0.75) FDPSALDH1A1TSHRMAPTSMN1; SMN2
3,4-Dimethoxybenzaldehyde SCHEMBL25202 0.83 ALDH1A1 (1.00) FDPSALDH1A1TSHRMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0273280-A2 Condensation polymer containing the residue of a poly-methine compound and shaped articles produced therefrom EASTMAN CHEMICAL COMPANY (US) 1988-07-06 EP disclosed
US-4749774-A UNSATURATED POLYESTERS EASTMAN KODAK COMPANY (US) 1988-06-07 US disclosed