SCHEMBL5599547

SCHEMBL5599547

COc1cc(C=O)ccc1OCC=C(C)C

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 2/20 0.75
TRPA1 O75762 1/20 0.75
PTGES O14684 6/20 0.69
FDPS P14324 1/20 0.67
ALDH1A1 P00352 5/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
TSHR P16473 1/20 0.62
POLB P06746 1/20 0.58
TRIM24 O15164 1/20 0.57
HPGD P15428 1/20 0.57
ALDH5A1 P51649 1/20 0.57
ABAT P80404 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
TRIM33 Q9UPN9 1/20 0.57
KDM4E B2RXH2 1/20 0.56
ALOX5 P09917 1/20 0.56
LMNA P02545 1/20 0.55
MAPT P10636 1/20 0.55
HTT P42858 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8846144 0.92 TRPA1 (0.63) MTNR1ATRPA1PTGESFDPSALDH1A1
SCHEMBL3573154 0.87 ALDH1A1 (0.66) MTNR1ATRPA1PTGESFDPSALDH1A1
Boropinal SCHEMBL18265488 0.86 MTNR1A (1.00) MTNR1ATRPA1PTGESFDPSPOLB
SCHEMBL30385438 0.85 FDPS (0.72) MTNR1ATRPA1PTGESFDPSALDH1A1
SCHEMBL25188487 0.85 FDPS (0.72) MTNR1ATRPA1PTGESFDPSALDH1A1
SCHEMBL10695955 0.84 FDPS (0.75) FDPSALDH1A1SMN1; SMN2TSHRPOLB
SCHEMBL10695943 0.84 FDPS (0.75) FDPSALDH1A1SMN1; SMN2TSHRPOLB
SCHEMBL17941258 0.84 FDPS (0.75) FDPSALDH1A1SMN1; SMN2TSHRPOLB
SCHEMBL18095848 0.83 ALDH1A1 (0.72) FDPSALDH1A1SMN1; SMN2TSHRPOLB
SCHEMBL3208266 0.83 PTGES (0.83) MTNR1ATRPA1PTGESFDPSALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210289794-A1 COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-09-23 US disclosed
EP-1764363-A2 SUBSTITUTED ACETOPHENONEDERIVATIVES Riemser Arzneimittel AG (DE) 2007-03-21 EP disclosed