Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.61 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692128 | 0.83 | ALOX5 (0.88) | ALOX5LTB4RLTB4R2 | |
| SCHEMBL10695836 | 0.83 | ALOX5 (0.88) | ALOX5LTB4RLTB4R2 | |
| SCHEMBL10695989 | 0.80 | ALOX5 (0.66) | ALOX5LTB4RLTB4R2TP53MAPT | |
| SCHEMBL10693993 | 0.76 | ALOX5 (1.00) | ALOX5LTB4RLTB4R2 | |
| SCHEMBL9022467 | 0.75 | LTB4R (0.80) | ALOX5LTB4RLTB4R2 | |
| SCHEMBL4315471 | 0.74 | HTR1A (0.53) | ALOX5PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL2576001 | 0.72 | DRD2 (0.57) | SLC1A5PTGER1HTR1ADRD2CARM1 | |
| SCHEMBL1462035 | 0.72 | HTR1A (0.57) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL31757878 | 0.72 | HTR1A (0.57) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL1007508 | 0.72 | CFD (0.68) | PTGER1PTGER4PTGER3PTGER2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792560-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | disclosed |