Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10696916 | 0.99 | DRD2 (0.46) | DRD2DRD3ADRA1AADRA1BHTR1A | |
| SCHEMBL10693226 | 0.88 | DRD3 (0.45) | DRD2DRD3HTR7 | |
| SCHEMBL10697140 | 0.84 | DRD3 (0.51) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL10696092 | 0.83 | DRD3 (0.50) | DRD2DRD3 | |
| SCHEMBL10695039 | 0.83 | OPRM1 (0.39) | DRD2DRD3 | |
| SCHEMBL10696248 | 0.81 | KCNA5 (0.45) | DRD2DRD3ALDH1A1KDM4E | |
| SCHEMBL10696548 | 0.80 | MEN1 (0.49) | DRD2DRD3ALDH1A1L3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL10696621 | 0.80 | KCNA5 (0.44) | DRD2DRD3ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL10696599 | 0.80 | MEN1 (0.48) | DRD2DRD3ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL7487266 | 0.77 | TACR1 (0.54) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252876-A1 | Hydrogenated 1-phenoxyalkylpyridine-3-carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | claimed |