SCHEMBL10697140

SCHEMBL10697140

COC(=O)OC1CN(CCOc2ccc(OC)cc2)CCC1=O

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 10/20 0.51
DRD2 P14416 5/20 0.51
LMNA P02545 1/20 0.46
TSHR P16473 1/20 0.46
KCNA5 P22460 4/20 0.45
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44
LTA4H P09960 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10696092 0.99 DRD3 (0.50) DRD3DRD2LMNATSHRKCNA5
SCHEMBL10696248 0.92 KCNA5 (0.45) DRD3DRD2LMNAKCNA5LTA4H
Hydrochloric Acid SCHEMBL10696621 0.91 KCNA5 (0.44) DRD3DRD2LMNAKCNA5LTA4H
SCHEMBL10696548 0.91 MEN1 (0.49) DRD3DRD2KCNA5LTA4H
Hydrochloric Acid SCHEMBL10696599 0.90 MEN1 (0.48) DRD3DRD2KCNA5LTA4H
SCHEMBL10693226 0.87 DRD3 (0.45) DRD3DRD2TSHR
SCHEMBL10695039 0.87 OPRM1 (0.39) DRD3DRD2
SCHEMBL10697263 0.84 DRD2 (0.47) DRD3DRD2
Hydrochloric Acid SCHEMBL10696916 0.84 DRD2 (0.46) DRD3DRD2
Hydrochloric Acid SCHEMBL10696100 0.80 KDM4E (0.50) DRD2LMNALTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0252876-A1 Hydrogenated 1-phenoxyalkylpyridine-3-carboxylic-acid compounds CIBA-GEIGY AG (CH) 1988-01-13 EP claimed