Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696298 | 0.86 | ALDH1A1 (0.34) | KDM4EGLAPLA2G7MAPTALDH1A1 | |
| SCHEMBL10696278 | 0.79 | EPAS1 (0.37) | MAPTALDH1A1LMNAHPGDMAPK1 | |
| SCHEMBL10696364 | 0.78 | EPAS1 (0.36) | MAPTALDH1A1HPGDMAPK1NPSR1 | |
| SCHEMBL10696732 | 0.74 | TXNRD1 (0.39) | KDM4EMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13731608 | 0.73 | MERTK (0.49) | KDM4EMAPTALDH1A1LMNANPC1 | |
| SCHEMBL10696366 | 0.72 | RAB9A (0.35) | KDM4EGLAMAPTMAOAALDH1A1 | |
| SCHEMBL10697439 | 0.72 | MEN1 (0.38) | KDM4EMAPTMAOAALDH1A1LMNA | |
| SCHEMBL10698024 | 0.71 | THRB (0.38) | KDM4EMAPTSMN1; SMN2PPARDTDP1 | |
| SCHEMBL10698177 | 0.71 | TDP1 (0.36) | MAPTALDH1A1HPGDMAPK1NPSR1 | |
| SCHEMBL2746717 | 0.69 | ALDH1A1 (0.51) | KDM4EGLAMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |