Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28447020 | 0.87 | TSHR (0.43) | TSHRTHRBALDH1A1HPGD | |
| Ether SCHEMBL4103771 | 0.85 | THRB (0.42) | TSHRTHRBALDH1A1 | |
| SCHEMBL35491 | 0.84 | TSHR (0.39) | TSHRALDH1A1 | |
| SCHEMBL28445118 | 0.84 | TSHR (0.51) | TSHRALDH1A1 | |
| SCHEMBL17968253 | 0.81 | TSHR (0.36) | TSHRTHRBALDH1A1 | |
| SCHEMBL2030266 | 0.80 | FAAH (0.35) | TSHR | |
| SCHEMBL9472415 | 0.80 | TSHR (0.36) | TSHRALDH1A1 | |
| Urethane SCHEMBL21483479 | 0.80 | ALOX15 (0.54) | ALOX15TSHRTHRBALDH1A1HPGD | |
| Methacrylic Acid SCHEMBL27993923 | 0.80 | TSHR (0.36) | TSHRALDH1A1 | |
| Urethane SCHEMBL4858633 | 0.79 | ALOX15 (0.52) | ALOX15TSHRTHRBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4721735-A | URETHANE MODIFIED ACRYLATES | DENTSPLY RESEARCH AND DEVELOPMENT CORPORATION (US) | 1988-01-26 | — | — | US | disclosed |