Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PTAFR | P25105 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695591 | 0.92 | PTAFR (0.48) | KMT2AGAAHTTSMN1; SMN2CRHBP | |
| SCHEMBL10694457 | 0.91 | KMT2A (0.46) | KMT2AGAAHTTSMN1; SMN2CRHBP | |
| SCHEMBL10695136 | 0.87 | PTAFR (0.51) | KMT2AGAAPTAFR | |
| SCHEMBL10642535 | 0.82 | CA1 (0.57) | KMT2AGAAHTTSMN1; SMN2CRHBP | |
| SCHEMBL28177089 | 0.81 | KMT2A (0.56) | KMT2AGAAHTTSMN1; SMN2CRHBP | |
| SCHEMBL8477516 | 0.81 | CYP11B2 (0.51) | SMN1; SMN2CYP11B1CYP11B2RAB9APTAFR | |
| SCHEMBL11792769 | 0.80 | GAA (0.52) | KMT2AGAAHTTSMN1; SMN2CRHBP | |
| SCHEMBL19090372 | 0.78 | TDP1 (0.57) | KMT2AGAACRHBPCRHR2PTAFR | |
| SCHEMBL18063436 | 0.78 | ALDH1A1 (0.58) | KMT2AHTTSMN1; SMN2MEN1RAB9A | |
| SCHEMBL7277594 | 0.77 | HTT (0.56) | KMT2AHTTSMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267439-A2 | Alpha-(phenylalkyl) pyridinealkanol derivatives | G.D. Searle & Co. (US) | 1988-05-18 | — | — | EP | claimed |
| EP-0267439-A2 | Alpha-(phenylalkyl) pyridinealkanol derivatives | G.D. Searle & Co. (US) | 1988-05-18 | — | — | EP | disclosed |